# Hit 1

Reference List

FA | IDE(1); FLST(13); XREF(3); INP(6); CDER(2); MP(9); CRYPH(2); NMR(1); IR(1); UV(2); MS(1); POT(1); FINFO(2); RX(4); CNR(20)

Substance (1 of 1)

Beilstein Registry Number | 90739
Beilstein Preferred RN | 94-62-2
CAS Registry Number | 94-62-2; 495-91-0; 7780-20-3; 30511-76-3; 30511-77-4
Chemical Name | 1-(5-benzo[1,3]dioxol-5-yl-penta-2,4-dienoyl)-piperidine; 1-Piperinoyl-piperidin; piperine
Autoname | 5-benzo[1,3]dioxol-5-yl-1-piperidin-1-yl-penta-2,4-dien-1-one
Molecular Formula | C17H19NO3
Molecular Weight | 285.34
Lawson Number | 24081; 22876
Compound Type | heterocyclic
Constitution ID | 38159
Tautomer ID | 14686
Beilstein Reference | 5-20-03-00469; 6-20
Entry Date | 1988/06/27
Update Date | 1994/01/18

Reference (1 of 20)

Citation Number | 119906
Document Type | Journal
Authors | Stoklosa,K.
CODEN | BSCFAS
Journal Title | Bull.Soc.Chim.Fr.
Language Code | FR
Publication Year | 1969
Page | 3802-3806

Reference (2 of 20)

Citation Number | 2605306
Document Type | Journal
Authors | Lloyd et al.
CODEN | JACSAT
Journal Title | J.Amer.Chem.Soc.
(Series) Volume | 82
Publication Year | 1960
Page | 3791

Reference (3 of 20)

Citation Number | 2835455
Document Type | Journal
Authors | Gupta et al.
CODEN | PYTCAS
Journal Title | Phytochemistry
(Series) Volume | 11
Publication Year | 1972
Page | 2646

Reference (4 of 20)

Citation Number | 3133321
Document Type | Journal
Authors | Dutta et al.
CODEN | IJSBDB
Journal Title | Indian J.Chem.Sect.B
(Series) Volume | 15
Publication Year | 1977
Page | 583

Reference (5 of 20)

Citation Number | 3133481
Document Type | Journal
Authors | Lurik et al.
CODEN | JGCHA4; ZOKHA4
Journal Title | J.Gen.Chem.USSR (Engl.Transl.); Zh.Obshch.Khim.
(Series) Volume | 45; 45
Publication Year | 1975; 1975
Page | 2246; 2287

Reference (6 of 20)

Citation Number | 3141536
Document Type | Journal
Authors | Mazeau; Zarzycki
CODEN | CHDCAQ
Journal Title | C.R.Hebd.Seances Acad.Sci.Ser.C
(Series) Volume | 281
Publication Year | 1975
Page | 583,584

Reference (7 of 20)

Citation Number | 3141959
Document Type | Journal
Authors | Loder et al.
CODEN | AJCHAS
Journal Title | Aust.J.Chem.
(Series) Volume | 22
Publication Year | 1969
Page | 1531,1538

Reference (8 of 20)

Citation Number | 3142215
Document Type | Journal
Authors | Banerji; Dhara
CODEN | PYTCAS
Journal Title | Phytochemistry
(Series) Volume | 13
Publication Year | 1974
Page | 2327

Reference (9 of 20)

Citation Number | 3142495
Document Type | Journal
Authors | Vashkov et al.
CODEN | RZKHAR
Journal Title | Ref.Zh.Khim.
Journal/Review Without CODEN | Chem.Abstr.
(Series) Volume | 17; 81
Number | 13234b
Publication Year | 1973; 1974
Page | 508

Reference (10 of 20)

Citation Number | 3214879
Document Type | Journal
Authors | Feugeas
CODEN | BSCFAS
Journal Title | Bull.Soc.Chim.Fr.
Publication Year | 1964
Page | 1892

Reference (11 of 20)

Citation Number | 3220501
Document Type | Journal
Authors | Normant; Feugeas
CODEN | COREAF
Journal Title | C.R.Hebd.Seances Acad.Sci.
(Series) Volume | 258
Publication Year | 1964
Page | 2846

Reference (12 of 20)

Citation Number | 3228104
Document Type | Journal
Authors | Graham
CODEN | JPMSAE
Journal Title | J.Pharm.Sci.
(Series) Volume | 54
Publication Year | 1965
Page | 319

Reference (13 of 20)

Citation Number | 3239881
Document Type | Journal
Authors | Mishra; Tewari
CODEN | JPMSAE
Journal Title | J.Pharm.Sci.
(Series) Volume | 53
Publication Year | 1964
Page | 1423

Reference (14 of 20)

Citation Number | 3281384
Document Type | Journal
Authors | Traxler
CODEN | JAFCAU
Journal Title | J.Agric.Food Chem.
(Series) Volume | 19
Publication Year | 1971
Page | 1135,1137

Reference (15 of 20)

Citation Number | 3341233
Document Type | Journal
Authors | Singh et al.
CODEN | JICSAH
Journal Title | J.Indian Chem.Soc.
(Series) Volume | 53
Publication Year | 1976
Page | 1162

Reference (16 of 20)

Citation Number | 3633748
Document Type | Journal
Authors | Bohnsack
CODEN | RSARAQ
Journal Title | Riechst.Aromen
(Series) Volume | 15
Publication Year | 1965
Page | 77

Reference (17 of 20)

Citation Number | 3678903
Document Type | Journal
Authors | Bordner; Mullins
CODEN | CSCMCS
Journal Title | Cryst.Struct.Commun.
(Series) Volume | 3
Publication Year | 1974
Page | 693

Reference (18 of 20)

Citation Number | 4815504
Document Type | Journal
Authors | Kulka
CODEN | JAFCAU
Journal Title | J.Agric.Food Chem.
(Series) Volume | 15
Publication Year | 1967
Page | 48,51

Reference (19 of 20)

Citation Number | 5546680
Document Type | Journal
Authors | Mandai, Tadakatsu; Moriyama, Tadashi; Tsujimoto, Koichiro; Kawada, Mikio; Otera, Junzo
CODEN | TELEAY
Journal Title | Tetrahedron Lett.
Language Code | EN
(Series) Volume | 27
Number | 5
Publication Year | 1986
Page | 603-606

Reference (20 of 20)

Citation Number | 5686470
Document Type | Journal
Authors | Hoelzel, Claus; Spiteller, Gerhard
CODEN | LACHDL
Journal Title | Liebigs Ann.Chem.
Language Code | GE
Number | 7
Publication Year | 1984
Page | 1319-1331

Reaction (1 of 4)

Reaction ID | 2627935
Reactant BRN | 4613019
Reactant | acetic acid 1-(benzenesulfonyl-benzo[1,3]dioxol-5-yl-methyl)-4-oxo-4-piperidin-1-yl-butyl ester
Product BRN | 90739; 90741
Product | 1-(5-benzo[1,3]dioxol-5-yl-penta-2,4-dienoyl)-piperidine; 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Reagent | t-BuOK
Solvent | 2-methyl-propan-2-ol
Time | 12 hour(s)
Other Conditions | Ambient temperature
Comment | Yield given. Yields of byproduct given
Citation Pointer | 5546680; Journal; Mandai, Tadakatsu; Moriyama, Tadashi; Tsujimoto, Koichiro; Kawada, Mikio; Otera, Junzo; TELEAY; Tetrahedron Lett.; EN; 27; 5; 1986; 603-606;

Reaction (2 of 4)

Reaction ID | 3863768
Reactant BRN | 90739
Reactant | 1-(5-benzo[1,3]dioxol-5-yl-penta-2,4-dienoyl)-piperidine
Product BRN | 5564597
Product | 5-(3,4-Dihydroxyphenyl)-2,4-pentadiensaeure-piperidid
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 86 percent (BRN=5564597)
Reagent | 0.5 M BBr3, 0.5 M sodium acetate buffer (pH=5)
Solvent | CH2Cl2
Time | 72 hour(s)
Other Conditions | Ambient temperature
Citation Pointer | 5686470; Journal; Hoelzel, Claus; Spiteller, Gerhard; LACHDL; Liebigs Ann.Chem.; GE; 7; 1984; 1319-1331;

Reaction (3 of 4)

Reaction ID | 5392514
Reactant BRN | 90739
Reactant | 1-(5-benzo[1,3]dioxol-5-yl-penta-2,4-dienoyl)-piperidine
No. of Reaction Details | 2
Reaction Classification | Chemical behaviour (half reaction)
Subject Studied | Kinetics
Citation Pointer | 119906; Journal; Stoklosa,K.; BSCFAS; Bull.Soc.Chim.Fr.; FR; 1969; 3802-3806;

Reaction (4 of 4)

Reaction ID | 5714783
Product BRN | 90739
Product | 1-(5-benzo[1,3]dioxol-5-yl-penta-2,4-dienoyl)-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation (half reaction)
Citation Pointer | 3220501; Journal; Normant; Feugeas; COREAF; C.R.Hebd.Seances Acad.Sci.; 258; 1964; 2846;3214879; Journal; Feugeas; BSCFAS; Bull.Soc.Chim.Fr.; 1964; 1892;

Isolation from Natural Product (1 of 6)

Isolation from Natural Product | aus Piper nigrum L.
Citation Pointer | 3281384; Journal; Traxler; JAFCAU; J.Agric.Food Chem.; 19; 1971; 1135,1137;

Isolation from Natural Product (2 of 6)

Isolation from Natural Product | aus Pfeffer
Citation Pointer | 3633748; Journal; Bohnsack; RSARAQ; Riechst.Aromen; 15; 1965; 77;

Isolation from Natural Product (3 of 6)

Isolation from Natural Product | aus Stengel von Piper nigrum Linn.
Citation Pointer | 3341233; Journal; Singh et al.; JICSAH; J.Indian Chem.Soc.; 53; 1976; 1162;

Isolation from Natural Product (4 of 6)

Isolation from Natural Product | aus Piper chaba
Citation Pointer | 3239881; Journal; Mishra; Tewari; JPMSAE; J.Pharm.Sci.; 53; 1964; 1423;

Isolation from Natural Product (5 of 6)

Isolation from Natural Product | aus Piper longum Linn.
Citation Pointer | 3133321; Journal; Dutta et al.; IJSBDB; Indian J.Chem.Sect.B; 15; 1977; 583;

Isolation from Natural Product (6 of 6)

Isolation from Natural Product | aus Piper nepalense
Citation Pointer | 2835455; Journal; Gupta et al.; PYTCAS; Phytochemistry; 11; 1972; 2646;

Derivative (1 of 2)

Comment | Hydrobromid: C17H19NO3*HBr: aus Piperin in Bzl., ges. benzol. HBr-Lsg.; F: 170grad
Citation Pointer | 3220501; Journal; Normant; Feugeas; COREAF; C.R.Hebd.Seances Acad.Sci.; 258; 1964; 2846;

Derivative (2 of 2)

Comment | Hydrobromid: F: 170grad (aus Bzl.; Kofler-App:)
Citation Pointer | 3214879; Journal; Feugeas; BSCFAS; Bull.Soc.Chim.Fr.; 1964; 1892;

Crossfile Reference (1 of 3)

Name | Piperine; for synthesis
Crossfile Source | E.Merck, Darmstadt
External Access ID | 821036

Crossfile Reference (2 of 3)

Name | PIPERINE, 97 PERCENT
Crossfile Source | Aldrich
External Access ID | P49007

Crossfile Reference (3 of 3)

Name | piperine
Crossfile Source | EINECS
External Access ID | 202-348-0

Melting Point (1 of 9)

Melting Point | 129.2 - 130.5
Citation Pointer | 3281384; Journal; Traxler; JAFCAU; J.Agric.Food Chem.; 19; 1971; 1135,1137;

Melting Point (2 of 9)

Melting Point | 129
Solvent | diethyl ether
Citation Pointer | 3220501; Journal; Normant; Feugeas; COREAF; C.R.Hebd.Seances Acad.Sci.; 258; 1964; 2846;3214879; Journal; Feugeas; BSCFAS; Bull.Soc.Chim.Fr.; 1964; 1892;

Melting Point (3 of 9)

Melting Point | 128
Citation Pointer | 119906; Journal; Stoklosa,K.; BSCFAS; Bull.Soc.Chim.Fr.; FR; 1969; 3802-3806;

Melting Point (4 of 9)

Melting Point | 128 - 129.5
Citation Pointer | 3142495; Journal; Vashkov et al.; RZKHAR; Ref.Zh.Khim.; 17; 1973; 508; Chem.Abstr.; 81; 13234b; 1974;3633748; Journal; Bohnsack; RSARAQ; Riechst.Aromen; 15; 1965; 77;

Melting Point (5 of 9)

Melting Point | 129 - 130
Citation Pointer | 2835455; Journal; Gupta et al.; PYTCAS; Phytochemistry; 11; 1972; 2646;

Melting Point (6 of 9)

Melting Point | 128 - 129
Citation Pointer | 4815504; Journal; Kulka; JAFCAU; J.Agric.Food Chem.; 15; 1967; 48,51;

Melting Point (7 of 9)

Melting Point | 127 - 129
Citation Pointer | 3142215; Journal; Banerji; Dhara; PYTCAS; Phytochemistry; 13; 1974; 2327;

Melting Point (8 of 9)

Melting Point | 128 - 129
Citation Pointer | 3133481; Journal; Lurik et al.; JGCHA4; J.Gen.Chem.USSR (Engl.Transl.); 45; 1975; 2246; ZOKHA4; Zh.Obshch.Khim.; 45; 1975; 2287;

Melting Point (9 of 9)

Melting Point | 120 - 129
Citation Pointer | 3341233; Journal; Singh et al.; JICSAH; J.Indian Chem.Soc.; 53; 1976; 1162;

Crystal Phase (1 of 2)

Description | Crystal habit
Citation Pointer | 3678903; Journal; Bordner; Mullins; CSCMCS; Cryst.Struct.Commun.; 3; 1974; 693;

Crystal Phase (2 of 2)

Description | Crystal growth
Citation Pointer | 3141536; Journal; Mazeau; Zarzycki; CHDCAQ; C.R.Hebd.Seances Acad.Sci.Ser.C; 281; 1975; 583,584;

Nuclear Magnetic Resonance (1 of 1)

Description | NMR
Citation Pointer | 3133481; Journal; Lurik et al.; JGCHA4; J.Gen.Chem.USSR (Engl.Transl.); 45; 1975; 2246; ZOKHA4; Zh.Obshch.Khim.; 45; 1975; 2287;

Infrared Spectra (1 of 1)

Description | IR
Citation Pointer | 3133481; Journal; Lurik et al.; JGCHA4; J.Gen.Chem.USSR (Engl.Transl.); 45; 1975; 2246; ZOKHA4; Zh.Obshch.Khim.; 45; 1975; 2287;3142215; Journal; Banerji; Dhara; PYTCAS; Phytochemistry; 13; 1974; 2327;3220501; Journal; Normant; Feugeas; COREAF; C.R.Hebd.Seances Acad.Sci.; 258; 1964; 2846;

Ultraviolet Spectra (1 of 2)

Description | Absorption maxima
Citation Pointer | 3220501; Journal; Normant; Feugeas; COREAF; C.R.Hebd.Seances Acad.Sci.; 258; 1964; 2846;

Ultraviolet Spectra (2 of 2)

Description | UV/VIS
Citation Pointer | 3133481; Journal; Lurik et al.; JGCHA4; J.Gen.Chem.USSR (Engl.Transl.); 45; 1975; 2246; ZOKHA4; Zh.Obshch.Khim.; 45; 1975; 2287;3281384; Journal; Traxler; JAFCAU; J.Agric.Food Chem.; 19; 1971; 1135,1137;

Mass Spectrum (1 of 1)

Citation Pointer | 3142215; Journal; Banerji; Dhara; PYTCAS; Phytochemistry; 13; 1974; 2327;

Electrochemical Characteristics (1 of 1)

Description | polarographic half-wave potential
Citation Pointer | 3133481; Journal; Lurik et al.; JGCHA4; J.Gen.Chem.USSR (Engl.Transl.); 45; 1975; 2246; ZOKHA4; Zh.Obshch.Khim.; 45; 1975; 2287;

Further Information (1 of 2)

Citation Pointer | 3141959; Journal; Loder et al.; AJCHAS; Aust.J.Chem.; 22; 1969; 1531,1538;3228104; Journal; Graham; JPMSAE; J.Pharm.Sci.; 54; 1965; 319;

Further Information (2 of 2)

Citation Pointer | 2605306; Journal; Lloyd et al.; JACSAT; J.Amer.Chem.Soc.; 82; 1960; 3791;

# Hit 2

Reference List

FA | IDE(1); FLST(23); XREF(4); RSTR(1); INP(30); CDER(1); CPD(2); MP(19); CRYPH(8); SP(1); DEN(4); DV(1); RI(1); NMR(15); IR(12); UV(10); MS(5); ELE(1); DE(3); POT(1); SLB(8); BSPM(1); PHARM(60); RX(31); CNR(126)

Substance (1 of 1)

Beilstein Registry Number | 90741
Beilstein Preferred RN | 94-62-2
CAS Registry Number | 94-62-2; 495-91-0; 7780-20-3; 30511-76-3; 30511-77-4
Chemical Name | 1-trans,trans-piperinoyl-piperidine; piperine; (E,E)-1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine
Autoname | 5-benzo[1,3]dioxol-5-yl-1-piperidin-1-yl-penta-2,4-dien-1-one
Molecular Formula | C17H19NO3
Molecular Weight | 285.34
Lawson Number | 24081; 22876
Structure Keyword | Stereo compound
Compound Type | heterocyclic
Constitution ID | 38159
Tautomer ID | 18563
Beilstein Reference | 0-20-00-00079; 1-20-00-00023; 2-20-00-00053; 4-20-00-01341; 5-20-03-00469; 6-20
Entry Date | 1988/06/27
Update Date | 2002/04/29

Reference (1 of 126)

Citation Number | 156361
Document Type | Journal
Authors | Okogun,J.I.; Ekong,D.E.U.
CODEN | JCPRB4
Journal Title | J.Chem.Soc.Perkin Trans.1
Language Code | EN
Publication Year | 1974
Page | 2195-2198

Reference (2 of 126)

Citation Number | 502948
Document Type | Journal
Authors | Peinemann
CODEN | ARPMAS
Journal Title | Arch.Pharm.(Weinheim Ger.)
(Series) Volume | 234
Publication Year | 1896
Page | 258

Reference (3 of 126)

Citation Number | 503101
Document Type | Journal
Authors | Fittig; Mielck
CODEN | JLACBF; JLACBF
Journal Title | Justus Liebigs Ann. Chem.; Justus Liebigs Ann. Chem.
(Series) Volume | 152; 172
Publication Year | 1869; 1874
Page | 52, 54; 140, 152

Reference (4 of 126)

Citation Number | 505033
Document Type | Journal
Authors | Borsche
CODEN | CHBEAM
Journal Title | Chem.Ber.
(Series) Volume | 44
Publication Year | 1911
Page | 2945

Reference (5 of 126)

Citation Number | 505376
Document Type | Journal
Authors | Dehn
CODEN | JACSAT
Journal Title | J.Amer.Chem.Soc.
(Series) Volume | 39
Publication Year | 1917
Page | 1400

Reference (6 of 126)

Citation Number | 505581
Document Type | Journal
Authors | Dobbie; Fox
CODEN | JCSOA9
Journal Title | J.Chem.Soc.
(Series) Volume | 103
Publication Year | 1913
Page | 1194

Reference (7 of 126)

Citation Number | 507531
Document Type | Journal
Authors | Lohaus
CODEN | JPCEAO
Journal Title | J.Prakt.Chem.
(Series) Volume | <2> 119
Publication Year | 1928
Page | 258

Reference (8 of 126)

Citation Number | 511899
Document Type | Journal
Authors | Briggs et al.
CODEN | ANCHAM
Journal Title | Anal.Chem.
(Series) Volume | 29
Publication Year | 1957
Page | 904, 905

Reference (9 of 126)

Citation Number | 520054
Document Type | Journal
Authors | Lohaus; Gall
CODEN | JLACBF
Journal Title | Justus Liebigs Ann. Chem.
(Series) Volume | 517
Publication Year | 1935
Page | 278, 284

Reference (10 of 126)

Citation Number | 529237
Document Type | Journal
Authors | Spring; Stark
CODEN | JCSOA9
Journal Title | J.Chem.Soc.
Publication Year | 1950
Page | 1177, 1178

Reference (11 of 126)

Citation Number | 536898
Document Type | Journal
Authors | Kopzik et al.
CODEN | VMUNAE
Journal Title | Vestn.Mosk.Univ.
Journal/Review Without CODEN | Chem.Abstr.
(Series) Volume | 13
Number | 6
Publication Year | 1958; 1959
Page | 91, 94; 15673

Reference (12 of 126)

Citation Number | 559145
Document Type | Journal
Authors | Wester
CODEN | CHZEA6
Journal Title | Chem.Zentralbl.
Language Code | GE
(Series) Volume | 86
Number | I
Publication Year | 1915
Page | 248

Reference (13 of 126)

Citation Number | 562634
Document Type | Journal
Authors | Pucher; Dehn
CODEN | JACSAT
Journal Title | J.Amer.Chem.Soc.
(Series) Volume | 43
Publication Year | 1921
Page | 1755

Reference (14 of 126)

Citation Number | 621663
Document Type | Journal
Authors | Skita; Franck
CODEN | CHBEAM
Journal Title | Chem.Ber.
(Series) Volume | 44
Publication Year | 1911
Page | 2866

Reference (15 of 126)

Citation Number | 625129
Document Type | Journal
Authors | Arnall
CODEN | JCSOA9
Journal Title | J.Chem.Soc.
(Series) Volume | 117
Publication Year | 1920
Page | 837

Reference (16 of 126)

Citation Number | 625734
Document Type | Journal
Authors | v. Weisse; Meyer-Levy
CODEN | JCPBAN; CHZEA6
Journal Title | J.Chim.Phys.Phys.Chim.Biol.; Chem.Zentralbl.
Language Code | GE
(Series) Volume | 14; 87
Number | II
Publication Year | 1916; 1916
Page | 276; 1030

Reference (17 of 126)

Citation Number | 625737
Document Type | Journal
Authors | Zeehuisen
CODEN | AEPPAE; CHZEA6
Journal Title | Naunyn-Schmiedeberg's Arch.Exp.Pathol.Pharmakol.; Chem.Zentralbl.
Language Code | GE
(Series) Volume | 86; 91
Number | III
Publication Year | 1920; 1920
Page | 366; 668

Reference (18 of 126)

Citation Number | 636409
Document Type | Journal
Authors | Janot; Chaigneau
CODEN | COREAF
Journal Title | C.R.Hebd.Seances Acad.Sci.
(Series) Volume | 225
Publication Year | 1947
Page | 1371

Reference (19 of 126)

Citation Number | 642911
Document Type | Journal
Authors | Pleat et al.
CODEN | JPHAA3
Journal Title | J.Am.Pharm.Assoc.
(Series) Volume | 40
Publication Year | 1951
Page | 107, 108

Reference (20 of 126)

Citation Number | 740972
Document Type | Journal
Authors | Kolthoff
CODEN | BIZEA2; PHJOAV; CHZEA6
Journal Title | Biochem.Z.; Pharm.J.; Chem.Zentralbl.
Language Code | GE
(Series) Volume | 162; 118; 98
Number | I
Publication Year | 1925; 1927
Page | 340; 126; 2116

Reference (21 of 126)

Citation Number | 745868
Document Type | Journal
Authors | Paterno
CODEN | GCITA9
Journal Title | Gazz.Chim.Ital.
(Series) Volume | 44 II
Publication Year | 1914
Page | 104, 106

Reference (22 of 126)

Citation Number | 784769
Document Type | Patent
Patent Author | Lever Brothers Co.
Patent Number | US 2085064
Patent Year | 1935

Reference (23 of 126)

Citation Number | 960841
Document Type | Journal
Authors | v. Babo; Keller
CODEN | JPCEAO; JCVWAE
Journal Title | J.Prakt.Chem.; Jahresber.Fortschr.Chem.Verw.Theile Anderer Wiss.
(Series) Volume | <1> 72
Publication Year | 1857; 1857
Page | 55; 413

Reference (24 of 126)

Citation Number | 960844
Document Type | Journal
Authors | Ruegheimer
CODEN | CHBEAM
Journal Title | Chem.Ber.
(Series) Volume | 15
Publication Year | 1882
Page | 1391

Reference (25 of 126)

Citation Number | 960845
Document Type | Journal
Authors | Peckolt
Journal/Review Without CODEN | Apoth. Ztg.
(Series) Volume | 10
Page | 471

Reference (26 of 126)

Citation Number | 960846
Document Type | Journal
Authors | Herlant
CODEN | PHJOAV
Journal Title | Pharm.J.
(Series) Volume | <3> 25
Page | 643

Reference (27 of 126)

Citation Number | 960847
Document Type | Journal
Authors | Stenhouse
CODEN | PHJOAV; JLACBF
Journal Title | Pharm.J.; Justus Liebigs Ann. Chem.
(Series) Volume | <1> 14; 95
Publication Year | 1855
Page | 363; 106

Reference (28 of 126)

Citation Number | 960848
Document Type | Journal
Authors | Wangerin
Journal/Review Without CODEN | Pharm. Ztg.
(Series) Volume | 48
Page | 454

Reference (29 of 126)

Citation Number | 960849
Document Type | Journal
Authors | Bauer; Hilger
CODEN | CHZEA6
Journal Title | Chem.Zentralbl.
Language Code | GE
(Series) Volume | 67
Number | I
Publication Year | 1896
Page | 1214

Reference (30 of 126)

Citation Number | 960850
Document Type | Journal
Authors | Varrentrapp; Will
CODEN | JLACBF
Journal Title | Justus Liebigs Ann. Chem.
(Series) Volume | 39
Publication Year | 1841
Page | 283

Reference (31 of 126)

Citation Number | 960851
Document Type | Journal
Authors | Regnault
CODEN | ANCPAC
Journal Title | Ann.Chim.(Paris)
(Series) Volume | <2> 68
Publication Year | 1838
Page | 158

Reference (32 of 126)

Citation Number | 960852
Document Type | Journal
Authors | Liebig
CODEN | JLACBF
Journal Title | Justus Liebigs Ann. Chem.
(Series) Volume | 6
Publication Year | 1833
Page | 36

Reference (33 of 126)

Citation Number | 960853
Document Type | Journal
Authors | Pelletier
CODEN | ANCPAC; JLACBF
Journal Title | Ann.Chim.(Paris); Justus Liebigs Ann. Chem.
(Series) Volume | <2> 51; 6
Publication Year | 1832; 1833
Page | 199; 33

Reference (34 of 126)

Citation Number | 960854
Document Type | Journal
Authors | Pelletier
CODEN | ANCPAC
Journal Title | Ann.Chim.(Paris)
Journal/Review Without CODEN | Schw.
(Series) Volume | <2> 16; 32
Publication Year | 1821
Page | 344; 436

Reference (35 of 126)

Citation Number | 960855
Document Type | Journal
Authors | Oerstedt
Journal/Review Without CODEN | Schweiggers Journ. f. Chemie u. Physik
(Series) Volume | 29
Page | 80

Reference (36 of 126)

Citation Number | 967599
Document Type | Journal
Authors | Skita; Meyer
CODEN | CHBEAM
Journal Title | Chem.Ber.
(Series) Volume | 45
Publication Year | 1912
Page | 3586

Reference (37 of 126)

Citation Number | 967610
Document Type | Journal
Authors | Tunmann
CODEN | CHZEA6
Journal Title | Chem.Zentralbl.
Language Code | GE
(Series) Volume | 89
Number | II
Publication Year | 1918
Page | 675

Reference (38 of 126)

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Publication Year | 1913
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Document Type | Journal
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Journal/Review Without CODEN | Chem.Abstr.
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Journal/Review Without CODEN | Trudy Dnetropetrovsk.chim.-technol.Inst.; Chem.Abstr.
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Citation Number | 981397
Document Type | Journal
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Journal/Review Without CODEN | Thermo-Mikro-Methoden,3.Aufl.
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Document Type | Journal
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Journal/Review Without CODEN | Chem.Abstr.
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Citation Number | 3714671
Document Type | Journal
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Document Type | Journal
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Citation Number | 5575872
Document Type | Journal
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Language Code | EN
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Citation Number | 5576619
Document Type | Journal
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Language Code | EN
(Series) Volume | 23
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Citation Number | 5597332
Document Type | Journal
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Language Code | GE
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Citation Number | 5673694
Document Type | Journal
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Language Code | EN
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Document Type | Journal
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Document Type | Journal
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Language Code | EN
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Citation Number | 5729448
Document Type | Journal
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CODEN | CPBTAL
Journal Title | Chem.Pharm.Bull.
Language Code | EN
(Series) Volume | 36
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Citation Number | 5739088
Document Type | Journal
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CODEN | JCPRB4
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Publication Year | 1983
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Citation Number | 5749938
Document Type | Journal
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Journal Title | Indian J.Chem.Sect.B
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Citation Number | 5753488
Document Type | Journal
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Citation Number | 5787666
Document Type | Journal
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Citation Number | 5825902
Document Type | Journal
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Citation Number | 5846053
Document Type | Journal
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Citation Number | 5851492
Document Type | Journal
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Citation Number | 5874363
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Document Type | Journal
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Language Code | EN
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Citation Number | 5942128
Document Type | Journal
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Language Code | EN
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Citation Number | 5945187
Document Type | Journal
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Citation Number | 5975360
Document Type | Journal
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Citation Number | 6049858
Document Type | Journal
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Citation Number | 6070238
Document Type | Journal
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Document Type | Journal
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Citation Number | 6225880
Document Type | Journal
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Citation Number | 6303567
Document Type | Journal
Authors | Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.
CODEN | PLMEAA
Journal Title | Planta Med.
Language Code | EN
(Series) Volume | 67
Number | 2
Publication Year | 2001
Page | 176 - 179

Reference (123 of 126)

Citation Number | 6303601
Document Type | Journal
Authors | Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.
CODEN | PLMEAA
Journal Title | Planta Med.
Language Code | EN
(Series) Volume | 67
Number | 3
Publication Year | 2001
Page | 284 - 287

Reference (124 of 126)

Citation Number | 6311443
Document Type | Journal
Authors | Schobert, Rainer; Siegfried, Sven; Gordon, Gary J.
CODEN | JCSPCE
Journal Title | J.Chem.Soc.Perkin Trans.1
Language Code | EN
Number | 19
Publication Year | 2001
Page | 2393 - 2397

Reference (125 of 126)

Citation Number | 6318024
Document Type | Journal
Authors | Sunkara, G.; Mada, S. R.; Vobalaboina, V.
CODEN | PHARAT
Journal Title | Pharmazie
Language Code | EN
(Series) Volume | 56
Number | 8
Publication Year | 2001
Page | 640 - 642

Reference (126 of 126)

Citation Number | 6320341
Document Type | Journal
Authors | Grainger, Richard S.; Procopio, Alberto; Steed, Jonathan W.
CODEN | ORLEF7
Journal Title | Org.Lett.
Language Code | EN
(Series) Volume | 3
Number | 22
Publication Year | 2001
Page | 3565 - 3568

Reaction (1 of 31)

Reaction ID | 1746488
Reactant BRN | 4327482; 1310620
Reactant | 2-(3,6-diisopropyl-pyrazine-2-sulfinyl)-1-piperidin-1-yl-ethanone; 5-(3-bromo-1-propenyl)-1,3-dioxaindan
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Reagent | 1.) potassium diisopropylamide (KDA)
Other Conditions | 1.) THF, hexane, RT, 1 h, 2.) THF, hexane, reflux
Comment | Yield given. Multistep reaction
Citation Pointer | 5535863; Journal; Ohta, Akihiro; Tonomura, Yoshiko; Sawaki, Junko; Naohito, Sato; Akiike, Hitomi; et al.; HTCYAM; Heterocycles; EN; 32; 5; 1991; 965-973;

Reaction (2 of 31)

Reaction ID | 1748676
Reactant BRN | 1365055; 131691
Reactant | N-2-butenoylpiperidine; benzo[1,3]dioxole-5-carbaldehyde
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 3
Reaction Classification | Chemical behaviour
Reagent | triethylbenzylammoniumchloride, 50percent KOH
Solvent | dimethylsulfoxide
Time | 2 hour(s)
Temperature | 60 - 65
Other Conditions | various solvents
Subject Studied | Product distribution
Citation Pointer | 5623047; Journal; Schulze, Andreas; Oediger, Hermann; LACHDL; Liebigs Ann.Chem.; GE; 9; 1981; 1725-1727;

Reaction (3 of 31)

Reaction ID | 1839034
Reactant BRN | 167676; 4416084
Reactant | 1-benzo[1,3]dioxol-5-yl-allyl alcohol; 1-p-tolylsulfanylethynyl-piperidine
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Other Conditions | 1.) BF3OEt2 in refluxing toluene; 2.) oxidation (m-chloroperbenzoic acid, CH2Cl2,-78 grad C); 3.) reflux in toluene
Comment | Yield given. Multistep reaction
Citation Pointer | 5542826; Journal; Nakai, Takeshi; Setoi, Hiroyuki; Kageyama, Yasuhide; TELEAY; Tetrahedron Lett.; EN; 22; 41; 1981; 4097-4100;

Reaction (4 of 31)

Reaction ID | 2627935
Reactant BRN | 4613019
Reactant | acetic acid 1-(benzenesulfonyl-benzo[1,3]dioxol-5-yl-methyl)-4-oxo-4-piperidin-1-yl-butyl ester
Product BRN | 90739; 90741
Product | 1-(5-benzo[1,3]dioxol-5-yl-penta-2,4-dienoyl)-piperidine; 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Reagent | t-BuOK
Solvent | 2-methyl-propan-2-ol
Time | 12 hour(s)
Other Conditions | Ambient temperature
Comment | Yield given. Yields of byproduct given
Citation Pointer | 5546680; Journal; Mandai, Tadakatsu; Moriyama, Tadashi; Tsujimoto, Koichiro; Kawada, Mikio; Otera, Junzo; TELEAY; Tetrahedron Lett.; EN; 27; 5; 1986; 603-606;

Reaction (5 of 31)

Reaction ID | 3829573
Reactant BRN | 85624; 102438
Reactant | trans,trans-piperinic acid; piperidine
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 2
Reaction Classification | Preparation
Yield | 90 percent (BRN=90741)
Reagent | N,N-bis(2-oxo-3-oxazolidinyl)phosphorodiamidic chloride, triethylamine
Solvent | CH2Cl2
Time | 60 min
Temperature | 20 - 25
Citation Pointer | 5571390; Journal; Cabre, Juan; Palomo, Antonio Luis; SYNTBF; Synthesis; EN; 5; 1984; 413-417;

Reaction (6 of 31)

Reaction ID | 3829578
Reactant BRN | 85625; 102438
Reactant | 5t-benzo[1,3]dioxol-5-yl-penta-2t,4-dienoyl chloride; piperidine
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 2
Reaction Classification | Preparation
Solvent | diethyl ether
Citation Pointer | 5576619; Journal; Banerji, Avijit; Ghosal, Tapasree; Acharyya, Aditi K.; IJSBDB; Indian J.Chem.Sect.B; EN; 23; 6; 1984; 546-549;

Reaction (7 of 31)

Reaction ID | 3863772
Reactant BRN | 1101343; 90741
Reactant | chloromalonic acid diethyl ester; 1-trans,trans-piperinoyl-piperidine
Product BRN | 1805352; 4894122
Product | ethenetetracarboxylic acid tetraethyl ester; 3-benzo[1,3]dioxol-5-yl-6-(piperidine-1-carbonyl)-3,6-dihydro-selenopyran-2,2-dicarboxylic acid diethyl ester
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 24 percent (BRN=4894122); 70 percent (BRN=1805352)
Reagent | selenium, Cs2CO3
Solvent | acetonitrile
Other Conditions | Heating
Citation Pointer | 5597332; Journal; Abelman, Matthew M.; TELEAY; Tetrahedron Lett.; EN; 32; 50; 1991; 7389-7392;

Reaction (8 of 31)

Reaction ID | 3863773
Reactant BRN | 1101343; 90741
Reactant | chloromalonic acid diethyl ester; 1-trans,trans-piperinoyl-piperidine
Product BRN | 4894108
Product | 3-benzo[1,3]dioxol-5-yl-6-(piperidine-1-carbonyl)-3,6-dihydro-thiopyran-2,2-dicarboxylic acid diethyl ester
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 80 percent (BRN=4894108)
Reagent | sulfur, Cs2CO3
Solvent | acetonitrile
Other Conditions | Heating
Citation Pointer | 5597332; Journal; Abelman, Matthew M.; TELEAY; Tetrahedron Lett.; EN; 32; 50; 1991; 7389-7392;

Reaction (9 of 31)

Reaction ID | 3863774
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 110253
Product | 1-nitroso-piperidine
No. of Reaction Details | 2
Reaction Classification | Preparation
Yield | 2.36 percent (BRN=110253)
Reagent | HClO4 (pH 3.0), NaNO2
Solvent | H2O
Time | 2 hour(s)
Temperature | 100
Citation Pointer | 5874363; Journal; Nakamura, Masamichi; Katoh, Kuni; Kawabata, Toshiharu; ABCHA6; Agric.Biol.Chem.; EN; 45; 5; 1981; 1257-1260;

Reaction (10 of 31)

Reaction ID | 3863775
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 288703
Product | 1-(5-benzo[1,3]dioxol-5-yl-pentanoyl)-piperidine
No. of Reaction Details | 4
Reaction Classification | Preparation
Reagent | H2
Catalyst | 10 percent Pd/C
Solvent | methanol
Time | 2 hour(s)
Pressure | 2585.74
Reaction Type | Catalytic hydrogenation
Citation Pointer | 6262921; Journal; Ablordeppey, Seth Y.; Fischer, James B.; Glennon, Richard A.; BMECEP; Bioorg.Med.Chem.; EN; 8; 8; 2000; 2105 - 2112;

Reaction (11 of 31)

Reaction ID | 3863776
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 6144494; 6168367
Product | Z-5-benzylidene-(3,4-methylenedioxy)-2(5H)-furanone; E,E-piperylpiperidine dimer
No. of Reaction Details | 3
Reaction Classification | Chemical behaviour
Yield | 26 percent (BRN=6144494); 30 percent (BRN=6168367)
Reagent | rose bengal
Solvent | methanol
Time | 18 hour(s)
Other Conditions | Irradiation
Subject Studied | Mechanism
Citation Pointer | 5753488; Journal; Kumar, Anil; Krupadanam, G L David; Srimannarayana, G; IJSBDB; Indian J.Chem.Sect.B; EN; 31; 11; 1992; 784-785;

Reaction (12 of 31)

Reaction ID | 3863777
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 6662570
Product | 4,5-(trans)-2,3-epoxy piperylpiperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 75 percent (BRN=6662570)
Reagent | 1percent H2O2
Time | 18 hour(s)
Temperature | 37
Other Conditions | Horseradish peroxidase, 0,1M sodium phosphate buffer, pH 6,5
Citation Pointer | 5851492; Journal; Rao, A. Bhaskar; Rao, M. Venkateswara; Kumar, Anil; Krupadanam, G. L. David; Srimannarayana, G.; TELEAY; Tetrahedron Lett.; EN; 35; 2; 1994; 279-280;

Reaction (13 of 31)

Reaction ID | 3863778
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 85624
Product | trans,trans-piperinic acid
No. of Reaction Details | 3
Reaction Classification | Preparation
Reagent | 10percent ethanolic NaOH
Solvent | ethanol
Citation Pointer | 5725528; Journal; Nakamura, Norio; Kiuchi, Fumiyuki; Tsuda, Yoshisuke; CPBTAL; Chem.Pharm.Bull.; EN; 36; 7; 1988; 2647-2651;

Reaction (14 of 31)

Reaction ID | 4925582
Reactant BRN | 7989620; 114442
Reactant | 5-(2-iodo-vinyl)-benzo[1,3]dioxole; 1-acryloyl-piperidine
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 38 percent (BRN=90741)
Reagent | palladium acetate, triphenylphosphine, lithium chloride, triethylamine
Solvent | acetonitrile
Time | 18 hour(s)
Temperature | 70 - 80
Citation Pointer | 6096589; Journal; Naskar, Dinabandhu; Chowdhury, Shantanu; Roy, Sujit; TELEAY; Tetrahedron Lett.; EN; 39; 7; 1998; 699-702;

Reaction (15 of 31)

Reaction ID | 4975527
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 8003486; 288703
Product | 5-benzo[1,3]dioxol-5-yl-1-piperidin-1-yl-pent-4-en-1-one; 1-(5-benzo[1,3]dioxol-5-yl-pentanoyl)-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 58 percent (BRN=288703); 14 percent (BRN=8003486)
Reagent | NaBH4 (0.008 mole), I2 (0.003 mole)
Solvent | tetrahydrofuran
Time | 20 min
Temperature | 0
Citation Pointer | 6096582; Journal; Das, Biswanath; Kashinatham, A.; Madhusudhan, P.; TELEAY; Tetrahedron Lett.; EN; 39; 7; 1998; 677-678;

Reaction (16 of 31)

Reaction ID | 4975528
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 8003486
Product | 5-benzo[1,3]dioxol-5-yl-1-piperidin-1-yl-pent-4-en-1-one
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 74 percent (BRN=8003486)
Reagent | NaBH4 (0.0025 mole), I2 (0.001 mole)
Solvent | tetrahydrofuran
Time | 20 min
Temperature | 0
Citation Pointer | 6096582; Journal; Das, Biswanath; Kashinatham, A.; Madhusudhan, P.; TELEAY; Tetrahedron Lett.; EN; 39; 7; 1998; 677-678;

Reaction (17 of 31)

Reaction ID | 5043968
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 8117956; 1261487
Product | 5-benzo[1,3]dioxol-5-yl-1-piperidin-1-yl-pent-3-en-1-one; trans-Db,g-Dihydro-piperidin
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 95 percent (BRN=1261487)
Reagent | Zn, HOAc
Time | 2 hour(s)
Other Conditions | Ambient temperature
Citation Pointer | 6117787; Journal; Das, Biswanath; Madhusudhan, P.; TELEAY; Tetrahedron Lett.; EN; 39; 49; 1998; 9099-9100;

Reaction (18 of 31)

Reaction ID | 5311563
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 1261487
Product | trans-Db,g-Dihydro-piperidin
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 96 percent (BRN=1261487)
Reagent | Mg; MeOH
Time | 2 hour(s)
Temperature | 20
Reaction Type | Reduction
Citation Pointer | 6209404; Journal; Das, Biswanth; Kashinatham, A.; Venkataiah, B.; SYNCAV; Synth.Commun.; EN; 29; 21; 1999; 3799 - 3804;

Reaction (19 of 31)

Reaction ID | 5392515
Reactant BRN | 1238185; 90741
Reactant | benzophenone; 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Chemical behaviour (half reaction)
Other Conditions | im Licht
Comment | Handbook
Citation Pointer | 745868; Journal; Paterno; GCITA9; Gazz.Chim.Ital.; 44 II; 1914; 104, 106;

Reaction (20 of 31)

Reaction ID | 5680972
Reactant BRN | 90741; 1718733
Reactant | 1-trans,trans-piperinoyl-piperidine; ethanol; phenylmercury-acetate
Product BRN | 53813
Product | 1-[5t-(6-phenylmercurio-benzo[1,3]dioxol-5-yl)-penta-2t,4-dienoyl]-piperidine
No. of Reaction Details | 2
Reaction Classification | Preparation
Comment | Handbook
Citation Pointer | 784769; Patent; Lever Brothers Co.; US 2085064; 1935;

Reaction (21 of 31)

Reaction ID | 5709607
Reactant BRN | 90741
Reactant | alcoholic KOH-solution; 1-trans,trans-piperinoyl-piperidine
Product BRN | 102438; 85624
Product | piperidine; trans,trans-piperinic acid
No. of Reaction Details | 1
Reaction Classification | Chemical behaviour
Comment | Handbook
Citation Pointer | 960841; Journal; v. Babo; Keller; JPCEAO; J.Prakt.Chem.; <1> 72; 1857; 55; JCVWAE; Jahresber.Fortschr.Chem.Verw.Theile Anderer Wiss.; 1857; 413;503101; Journal; Fittig; Mielck; JLACBF; Justus Liebigs Ann. Chem.; 152; 1869; 52, 54; JLACBF; Justus Liebigs Ann. Chem.; 172; 1874; 140, 152;

Reaction (22 of 31)

Reaction ID | 5714786
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation (half reaction)
Citation Pointer | 3132215; Journal; Tsuboi; Takeda; TELEAY; Tetrahedron Lett.; 1979; 1043;3140982; Journal; Grewe et al.; CHBEAM; Chem.Ber.; 103; 1970; 3752,3766;3141492; Journal; Lurik et al.; PCJOAU; Pharm.Chem.J.(Engl.Transl.); 5; 8; 1971; 462; KHFZAN; Khim.Farm.Zh.; 5; 8; 1971; 15;2995721; Patent; Haarmann and Reimer; DE 2757506; 1977;

Reaction (23 of 31)

Reaction ID | 5714787
Reactant BRN | 102438
Reactant | chavicinoyl chloride; piperidine
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Comment | Handbook
Citation Pointer | 520054; Journal; Lohaus; Gall; JLACBF; Justus Liebigs Ann. Chem.; 517; 1935; 278, 284;507531; Journal; Lohaus; JPCEAO; J.Prakt.Chem.; <2> 119; 1928; 258;

Reaction (24 of 31)

Reaction ID | 5714788
Reactant BRN | 102438
Reactant | piperidine; piperinic acid chloride
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Reagent | benzene
Comment | Handbook
Citation Pointer | 960844; Journal; Ruegheimer; CHBEAM; Chem.Ber.; 15; 1882; 1391;

Reaction (25 of 31)

Reaction ID | 5746581
Reactant BRN | 1718733; 90741
Reactant | ethanol; hydrogen; colloidal palladium; 1-trans,trans-piperinoyl-piperidine
Product | tetrahydropiperine
No. of Reaction Details | 1
Reaction Classification | Chemical behaviour (half reaction)
Comment | Handbook
Citation Pointer | 505033; Journal; Borsche; CHBEAM; Chem.Ber.; 44; 1911; 2945;967599; Journal; Skita; Meyer; CHBEAM; Chem.Ber.; 45; 1912; 3586;1310037; Journal; Paal; CHBEAM; Chem.Ber.; 45; 1912; 2226;

Reaction (26 of 31)

Reaction ID | 5746582
Reactant BRN | 1098214; 90741
Reactant | hydrogen; hydrochloric acid; palladium chloride; 1-trans,trans-piperinoyl-piperidine
Product | tetrahydropiperine
No. of Reaction Details | 1
Reaction Classification | Chemical behaviour (half reaction)
Comment | Handbook
Citation Pointer | 621663; Journal; Skita; Franck; CHBEAM; Chem.Ber.; 44; 1911; 2866;

Reaction (27 of 31)

Reaction ID | 5746583
Reactant BRN | 1098214; 90741
Reactant | hydrogen; hydrochloric acid; platinum chlorides; 1-trans,trans-piperinoyl-piperidine
Product | tetrahydropiperine
No. of Reaction Details | 1
Reaction Classification | Chemical behaviour (half reaction)
Comment | Handbook
Citation Pointer | 621663; Journal; Skita; Franck; CHBEAM; Chem.Ber.; 44; 1911; 2866;

Reaction (28 of 31)

Reaction ID | 8539764
Reactant BRN | 84600; 114442
Reactant | 3-benzo[1,3]dioxol-5-yl-acrylic acid; 1-acryloyl-piperidine
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Multistage
Yield | 51 percent (BRN=90741)
No. of Stages | 2
Stage 1 |
Stage 2 |
Stage Reactant BRN | 114442
Stage Reactant | 1-acryloyl-piperidine
Reagent | N-bromosuccinimide; tetrabutylammonium trifluoroacetate; Pd(OAc)2; Ph3Sb; Et3N
Solvent | 1,2-dichloro-ethane; 1,2-dichloro-ethane
Time | 4 hour(s); 20 hour(s)
Temperature | 20
Reaction Type | Decarboxylation; bromination; Hunsdiecker reaction; Heck reaction
Citation Pointer | 6225104; Journal; Naskar, Dinabandhu; Roy, Sujit; TETRAB; Tetrahedron; EN; 56; 10; 2000; 1369 - 1378;

Reaction (29 of 31)

Reaction ID | 8735157
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 8705257
Product | 1-[1-(3,4-methylenedioxyphenyl)-2,4-pentadienyl]piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Reagent | LiAlH4
Solvent | diethyl ether
Time | 24 hour(s)
Other Conditions | Heating
Reaction Type | Reduction
Citation Pointer | 6262921; Journal; Ablordeppey, Seth Y.; Fischer, James B.; Glennon, Richard A.; BMECEP; Bioorg.Med.Chem.; EN; 8; 8; 2000; 2105 - 2112;

Reaction (30 of 31)

Reaction ID | 8900343
Reactant BRN | 7622; 2811397; 102438
Reactant | 3,4-methylenedioxy-trans-cinnamaldehyde; (triphenylphosphoranylidene)ethenone; piperidine
Product BRN | 90741
Product | 1-trans,trans-piperinoyl-piperidine
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 90 percent (BRN=90741)
Solvent | tetrahydrofuran
Time | 24 hour(s)
Other Conditions | Heating
Citation Pointer | 6311443; Journal; Schobert, Rainer; Siegfried, Sven; Gordon, Gary J.; JCSPCE; J.Chem.Soc.Perkin Trans.1; EN; 19; 2001; 2393 - 2397;

Reaction (31 of 31)

Reaction ID | 8986873
Reactant BRN | 90741
Reactant | 1-trans,trans-piperinoyl-piperidine
Product BRN | 8998762
Product | (5-benzo[1,3]dioxol-5-yl-thiophen-2-yl)-piperidin-1-yl-methanone
No. of Reaction Details | 1
Reaction Classification | Preparation
Yield | 23 percent (BRN=8998762)
Reagent | naphthalene-1,8-trisulfide-2-oxide
Solvent | chlorobenzene
Time | 16 hour(s)
Other Conditions | Heating
Citation Pointer | 6320341; Journal; Grainger, Richard S.; Procopio, Alberto; Steed, Jonathan W.; ORLEF7; Org.Lett.; EN; 3; 22; 2001; 3565 - 3568;

Isolation from Natural Product (1 of 30)

Isolation from Natural Product | oleoresin, extract from fruits of Piper nigrum L. (Piperaceae)
Citation Pointer | 6303567; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 2; 2001; 176 - 179;

Isolation from Natural Product (2 of 30)

Isolation from Natural Product | stems of Piper tuberculatum
Citation Pointer | 6264052; Journal; Navickiene, Hosana Maria D.; Alecio, Alberto Camilo; Kato, Massuo Jorge; Bolzani, Vanderlan da S.; Young, Maria Claudia M.; Cavalheiro, Alberto Jose; Furlan, Maysa; PYTCAS; Phytochemistry; EN; 55; 2410; 2000; 621 - 626;

Isolation from Natural Product (3 of 30)

Isolation from Natural Product | dry fruits of black pepper
Citation Pointer | 6225880; Journal; Paula, Vanderlucia F. de; A Barbosa, Luiz C. de; Demuner, Antonio J.; Pilo-Veloso, Dorila; Picanco, Marcelo C.; PMSCFC; Post Manage.Sci.; EN; 56; 2; 2000; 168 - 174;

Isolation from Natural Product (4 of 30)

Isolation from Natural Product | fruits of Piper retrofractum Vahl.
Citation Pointer | 6205590; Journal; Pande, Archana; Shukla, Y. N.; Srivastava, Ritu; Verma, Monika; IJSBDB; Indian J.Chem.Sect.B; EN; 36; 4; 1997; 377 - 379;

Isolation from Natural Product (5 of 30)

Isolation from Natural Product | the fruits of Piper Longum Linn (Piperaceae)
Citation Pointer | 6161595; Journal; Das, B.; Kashinatham, A.; Madhusudhan, P.; BCFAAI; Boll.Chim.Farm.; EN; 137; 8; 1998; 319 - 320;

Isolation from Natural Product (6 of 30)

Isolation from Natural Product | leaves of Piper betle
Citation Pointer | 6124808; Journal; Parmar, Virinder S.; Jain, Subhash C.; Gupta, Sangita; Talwar, Sangeeta; Rajwanshi, Vivek K.; et al.; PYTCAS; Phytochemistry; EN; 49; 4; 1998; 1069-1078;

Isolation from Natural Product (7 of 30)

Isolation from Natural Product | stems and leaves of Piper khasiana, Piper thomsoni, Piper acutislegnum
Citation Pointer | 6124808; Journal; Parmar, Virinder S.; Jain, Subhash C.; Gupta, Sangita; Talwar, Sangeeta; Rajwanshi, Vivek K.; et al.; PYTCAS; Phytochemistry; EN; 49; 4; 1998; 1069-1078;

Isolation from Natural Product (8 of 30)

Isolation from Natural Product | Piper acutisleginum, Piperle, Piper khasiana
Citation Pointer | 6080863; Journal; Parmar, Virinder S.; Jain, Subhash C.; Bisht, Kirpal S.; Jain, Pajni; Taneja, Poonam; et al.; PYTCAS; Phytochemistry; EN; 46; 4; 1997; 597-674;

Isolation from Natural Product (9 of 30)

Isolation from Natural Product | fruits of Piper nigrum
Citation Pointer | 6070238; Journal; Siddiqui, Bina S.; Begum, Sabira; Gulzar, Tahsin; Noor, Farhat and Fatima; PYTCAS; Phytochemistry; EN; 45; 8; 1997; 1617-1620;

Isolation from Natural Product (10 of 30)

Isolation from Natural Product | fruits of Piper longum L. (Piperaceae), climber from India
Citation Pointer | 6049858; Journal; Das, Biswanath; Kashinatham, A.; Srinivas, K. V. N. S.; PLMEAA; Planta Med.; EN; 62; 6; 1996; 582;

Isolation from Natural Product (11 of 30)

Isolation from Natural Product | black pepper at 294 bar and 42 deg C, extracted with CO2
Citation Pointer | 5945187; Journal; Braumann, Urich; Haendel, heidrun; Albert, Klaus; Ecker, Rainer; Spraul, Manfred; ANCHAM; Anal.Chem.; EN; 67; 5; 1995; 930-935;

Isolation from Natural Product (12 of 30)

Isolation from Natural Product | fruits of white pepper (Piper nigrum L.)
Citation Pointer | 5874394; Journal; Nakatani, Nobuji; Inatani, Reiko; ABCHA6; Agric.Biol.Chem.; EN; 45; 6; 1981; 1473-1476;

Isolation from Natural Product (13 of 30)

Isolation from Natural Product | Piper nigrum L.
Citation Pointer | 5874363; Journal; Nakamura, Masamichi; Katoh, Kuni; Kawabata, Toshiharu; ABCHA6; Agric.Biol.Chem.; EN; 45; 5; 1981; 1257-1260;

Isolation from Natural Product (14 of 30)

Isolation from Natural Product | Ulocladium sp.
Citation Pointer | 5864041; Journal; Dahiya, Jagroop S.; Woods, Donald L.; Tewari, Jalpa P.; PYTCAS; Phytochemistry; EN; 27; 7; 1988; 2366;

Isolation from Natural Product (15 of 30)

Isolation from Natural Product | fruits of Javanese long pepper, Piper retrofractum Vahl.
Citation Pointer | 5846053; Journal; Kikuzaki, Hiroe; Kawabata, Marona; Ishida, Etsuko; Akazawa, Yoko; Takei, Yoko; et al.; BBBIEJ; Biosci.Biotechnol.Biochem.; EN; 57; 8; 1993; 1329-1333;

Isolation from Natural Product (16 of 30)

Isolation from Natural Product | Anethum sowa (seeds)
Citation Pointer | 5749938; Journal; Jain, A. K.; Sharma, N. D.; Gupta, S. R.; IJSBDB; Indian J.Chem.Sect.B; EN; 25; 1986; 979;

Isolation from Natural Product (17 of 30)

Isolation from Natural Product | pepper, fruits of Piper nigrum L.
Citation Pointer | 5729448; Journal; Kiuchi, Fumiyuki; Nakamura, Norio; Tsuda, Yoshisuke; Kondo, Kaoru; Yoshimura, Hiroyuki; CPBTAL; Chem.Pharm.Bull.; EN; 36; 7; 1988; 2452-2465;

Isolation from Natural Product (18 of 30)

Isolation from Natural Product | Piper retrofractum (Piperaceae)
Citation Pointer | 5710925; Journal; Ahn, Jong-Woong; Ahn, Mi-Ja; Zee, Ok-Pyo; Kim, Eun-Joo; Lee, Sueg-Geun; et al.; PYTCAS; Phytochemistry; EN; 31; 10; 1992; 3609-3612;

Isolation from Natural Product (19 of 30)

Isolation from Natural Product | fruits of Piper longum L.
Citation Pointer | 5673694; Journal; Tabuneng, Wnanbyr; Bando, Hideo; Amiya, Takashi; CPBTAL; Chem.Pharm.Bull.; EN; 31; 10; 1983; 3562-3565;

Isolation from Natural Product (20 of 30)

Isolation from Natural Product | Piper argyrophyllum Miq.
Citation Pointer | 5575872; Journal; Banerji, Avijit; Nandi, Gopa; IJSBDB; Indian J.Chem.Sect.B; EN; 27; 1-12; 1988; 163-165;

Isolation from Natural Product (21 of 30)

Isolation from Natural Product | Piper nigrum L.
Citation Pointer | 5510783; Journal; Das, B. P.; Jamal, Molla Yousuf; Choudhury, B.; JICSAH; J.Indian Chem.Soc.; EN; 67; 1; 1990; 72-73;

Isolation from Natural Product (22 of 30)

Isolation from Natural Product | Vork. u. Isol. aus Piper peepuloides
Citation Pointer | 3143698; Journal; Dhar; Raina; PLMEAA; Planta Med.; 23; 1973; 295,296;

Isolation from Natural Product (23 of 30)

Isolation from Natural Product | aus schwarzem Pfeffer
Citation Pointer | 3141492; Journal; Lurik et al.; PCJOAU; Pharm.Chem.J.(Engl.Transl.); 5; 8; 1971; 462; KHFZAN; Khim.Farm.Zh.; 5; 8; 1971; 15;

Isolation from Natural Product (24 of 30)

Isolation from Natural Product | aus Papaver aurantiacum
Citation Pointer | 3132150; Journal; Madhusudhana et al.; CUSCAM; Curr.Sci.; 43; 1974; 76;

Isolation from Natural Product (25 of 30)

Isolation from Natural Product | aus Fruechten von Piper guineense
Citation Pointer | 156361; Journal; Okogun,J.I.; Ekong,D.E.U.; JCPRB4; J.Chem.Soc.Perkin Trans.1; EN; 1974; 2195-2198;

Isolation from Natural Product (26 of 30)

Isolation from Natural Product | Findet sich in den unreifen Fruechten ('schwarzer Pfeffer') und in den Kernen der reifen Fruechte ('weisser Pfeffer') von Piper nigrum
Comment | Handbook
Citation Pointer | 960850; Journal; Varrentrapp; Will; JLACBF; Justus Liebigs Ann. Chem.; 39; 1841; 283;960851; Journal; Regnault; ANCPAC; Ann.Chim.(Paris); <2> 68; 1838; 158;960852; Journal; Liebig; JLACBF; Justus Liebigs Ann. Chem.; 6; 1833; 36;960853; Journal; Pelletier; ANCPAC; Ann.Chim.(Paris); <2> 51; 1832; 199; JLACBF; Justus Liebigs Ann. Chem.; 6; 1833; 33;960854; Journal; Pelletier; ANCPAC; Ann.Chim.(Paris); <2> 16; 1821; 344; Schw.; 32; 436;960855; Journal; Oerstedt; Schweiggers Journ. f. Chemie u. Physik; 29; 80;

Isolation from Natural Product (27 of 30)

Isolation from Natural Product | Findet sich ferner im langen Pfeffer (reife Fruechte von P. longum und P. officinarum)
Comment | Handbook
Citation Pointer | 960848; Journal; Wangerin; Pharm. Ztg.; 48; 454;960849; Journal; Bauer; Hilger; CHZEA6; Chem.Zentralbl.; GE; 67; I; 1896; 1214;

Isolation from Natural Product (28 of 30)

Isolation from Natural Product | in den Fruechten von P. Clusii (Aschantipfeffer)
Comment | Handbook
Citation Pointer | 960846; Journal; Herlant; PHJOAV; Pharm.J.; <3> 25; 643;960847; Journal; Stenhouse; PHJOAV; Pharm.J.; <1> 14; 363; JLACBF; Justus Liebigs Ann. Chem.; 95; 1855; 106;

Isolation from Natural Product (29 of 30)

Isolation from Natural Product | in der Wurzelrinde von Artanthe geniculata (unechte Jaborandi)
Comment | Handbook
Citation Pointer | 960845; Journal; Peckolt; Apoth. Ztg.; 10; 471;

Isolation from Natural Product (30 of 30)

Isolation from Natural Product | in den Fruechten von P. Lowong
Comment | Handbook
Citation Pointer | 502948; Journal; Peinemann; ARPMAS; Arch.Pharm.(Weinheim Ger.); 234; 1896; 258;

Derivative (1 of 1)

Derivative BRN | 288703
Derivative | 1-(5-benzo[1,3]dioxol-5-yl-pentanoyl)-piperidine
Citation Pointer | 5749938; Journal; Jain, A. K.; Sharma, N. D.; Gupta, S. R.; IJSBDB; Indian J.Chem.Sect.B; EN; 25; 1986; 979;

Related Structure (1 of 1)

Citation Pointer | 3635101; Journal; De Cleyn; Verzele; BSCBAG; Bull.Soc.Chim.Belg.; 84; 1975; 435,436;

Crossfile Reference (1 of 4)

Name | Piperine, purum
Crossfile Source | Fluka
External Access ID | 80810

Crossfile Reference (2 of 4)

Name | Piperidine, 1-<5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl>-, (E,E)-
Crossfile Source | CRC Handbook of Chemistry and Physics
External Access ID | 20134

Crossfile Reference (3 of 4)

Data Type | 13C-NMR Spectrum
Crossfile Source | CSEARCH
External Access ID | SADT-12317

Crossfile Reference (4 of 4)

Data Type | 13C-NMR Spectrum
Crossfile Source | CSEARCH
External Access ID | UNIW-14585

Crystal Property Description (1 of 2)

Colour & Other Properties | light-yellow
Citation Pointer | 6311443; Journal; Schobert, Rainer; Siegfried, Sven; Gordon, Gary J.; JCSPCE; J.Chem.Soc.Perkin Trans.1; EN; 19; 2001; 2393 - 2397;

Crystal Property Description (2 of 2)

Colour & Other Properties | Prismen
Comment | Handbook
Citation Pointer | 967610; Journal; Tunmann; CHZEA6; Chem.Zentralbl.; GE; 89; II; 1918; 675;

Melting Point (1 of 19)

Solvent | ethyl acetate
Comment | Handbook
Citation Pointer | 967610; Journal; Tunmann; CHZEA6; Chem.Zentralbl.; GE; 89; II; 1918; 675;

Melting Point (2 of 19)

Melting Point | 131
Solvent | diethyl ether
Citation Pointer | 5749938; Journal; Jain, A. K.; Sharma, N. D.; Gupta, S. R.; IJSBDB; Indian J.Chem.Sect.B; EN; 25; 1986; 979;

Melting Point (3 of 19)

Melting Point | 132
Solvent | benzene
Citation Pointer | 3132150; Journal; Madhusudhana et al.; CUSCAM; Curr.Sci.; 43; 1974; 76;

Melting Point (4 of 19)

Melting Point | 130
Citation Pointer | 5575872; Journal; Banerji, Avijit; Nandi, Gopa; IJSBDB; Indian J.Chem.Sect.B; EN; 27; 1-12; 1988; 163-165;

Melting Point (5 of 19)

Melting Point | 130
Citation Pointer | 3143698; Journal; Dhar; Raina; PLMEAA; Planta Med.; 23; 1973; 295,296;

Melting Point (6 of 19)

Melting Point | 129.5
Comment | Handbook
Citation Pointer | 502948; Journal; Peinemann; ARPMAS; Arch.Pharm.(Weinheim Ger.); 234; 1896; 258;

Melting Point (7 of 19)

Melting Point | 129.5
Comment | Handbook
Citation Pointer | 981397; Journal; Kofler,L.u.A.; Thermo-Mikro-Methoden,3.Aufl.; <Weinheim 1954> S.471;

Melting Point (8 of 19)

Melting Point | 127
Citation Pointer | 5975360; Journal; Dehmlow, Eckehard V.; Shamout, Abdul Rahman; JRMPDM; J.Chem.Res.Miniprint; GE; 4; 1981; 1178-1184;

Melting Point (9 of 19)

Melting Point | 129
Citation Pointer | 5874394; Journal; Nakatani, Nobuji; Inatani, Reiko; ABCHA6; Agric.Biol.Chem.; EN; 45; 6; 1981; 1473-1476;

Melting Point (10 of 19)

Melting Point | 128
Citation Pointer | 5576619; Journal; Banerji, Avijit; Ghosal, Tapasree; Acharyya, Aditi K.; IJSBDB; Indian J.Chem.Sect.B; EN; 23; 6; 1984; 546-549;

Melting Point (11 of 19)

Melting Point | 129
Citation Pointer | 3143025; Journal; Patra; Gosh; PYTCAS; Phytochemistry; 13; 1974; 2889;3635101; Journal; De Cleyn; Verzele; BSCBAG; Bull.Soc.Chim.Belg.; 84; 1975; 435,436;

Melting Point (12 of 19)

Melting Point | 128
Citation Pointer | 3140982; Journal; Grewe et al.; CHBEAM; Chem.Ber.; 103; 1970; 3752,3766;

Melting Point (13 of 19)

Melting Point | 128.5 - 130
Citation Pointer | 3714671; Journal; Meerov; Katyuzhanskaya; CHNCA8; Chem.Nat.Compd.(Engl.Transl.); 9; 1973; 179; KPSUAR; Khim.Prir.Soedin.; 9; 1973; 184;

Melting Point (14 of 19)

Melting Point | 129 - 130
Citation Pointer | 2995721; Patent; Haarmann and Reimer; DE 2757506; 1977;

Melting Point (15 of 19)

Melting Point | 128 - 129.5
Citation Pointer | 3141492; Journal; Lurik et al.; PCJOAU; Pharm.Chem.J.(Engl.Transl.); 5; 8; 1971; 462; KHFZAN; Khim.Farm.Zh.; 5; 8; 1971; 15;

Melting Point (16 of 19)

Melting Point | 128 - 130
Citation Pointer | 156361; Journal; Okogun,J.I.; Ekong,D.E.U.; JCPRB4; J.Chem.Soc.Perkin Trans.1; EN; 1974; 2195-2198;

Melting Point (17 of 19)

Melting Point | 128 - 129.5
Comment | Handbook
Citation Pointer | 960844; Journal; Ruegheimer; CHBEAM; Chem.Ber.; 15; 1882; 1391;

Melting Point (18 of 19)

Melting Point | 128 - 129
Citation Pointer | 6070238; Journal; Siddiqui, Bina S.; Begum, Sabira; Gulzar, Tahsin; Noor, Farhat and Fatima; PYTCAS; Phytochemistry; EN; 45; 8; 1997; 1617-1620;

Melting Point (19 of 19)

Melting Point | 124
Citation Pointer | 6205590; Journal; Pande, Archana; Shukla, Y. N.; Srivastava, Ritu; Verma, Monika; IJSBDB; Indian J.Chem.Sect.B; EN; 36; 4; 1997; 377 - 379;

Crystal Phase (1 of 8)

Description | Rate of crystallization
Comment | von unterkuehltem Piperin bei verschiedenen Temperaturen.; Handbook
Citation Pointer | 969754; Journal; Tammann; ZEPCAC; Z.Phys.Chem.Stoechiom.Verwandtschaftsl.; 25; 1894; 450; ZAACAB; Z.Anorg.Allg.Chem.; 181; 1929; 413;

Crystal Phase (2 of 8)

Description | Rate of crystallization
Comment | von unterkuehltem Piperidin bei Drucken bis 1000 kg/cm2.; Handbook
Citation Pointer | 969753; Journal; Hasselblatt; ZAACAB; Z.Anorg.Allg.Chem.; 119; 1921; 361;

Crystal Phase (3 of 8)

Description | Rate of crystallization
Comment | Geschwindigkeit der Bildung von Keimen bei der Kristallisation von unterkuehlten Schmelzen bei 20grad bzw. bei 48grad:.; Handbook
Citation Pointer | 981393; Journal; Kondoguri; ZETFA7; Zh.Eksp.Teor.Fiz.; 11; 1941; 728; Chem.Abstr.; 1943; 1314;2200674; Journal; Michnewitsch; KOZHAG; Kolloidn.Zh.; 21; 1959; 69; engl. Ausg. S. 61;

Crystal Phase (4 of 8)

Description | Rate of crystallization
Comment | Keimbildung bei der Kristallisation von unterkuehlten Schmelzen in Abhaengigkeit von der Temperatur (72-80grad):.; Handbook
Citation Pointer | 2175033; Journal; Tammann; Elsner v. Gronow; ZAACAB; Z.Anorg.Allg.Chem.; 200; 1931; 57, 68;

Crystal Phase (5 of 8)

Description | Rate of crystallization
Comment | in Abhaengigkeit von der Temperatur(0gradbis 90grad) und vom Reinheitsgrad:.; Handbook
Citation Pointer | 981393; Journal; Kondoguri; ZETFA7; Zh.Eksp.Teor.Fiz.; 11; 1941; 728; Chem.Abstr.; 1943; 1314;

Crystal Phase (6 of 8)

Description | Rate of crystallization
Comment | Verstaerkte Keimbildung bei der Kristallisation von unterkuehlten Schmelzen bei Einwirkung von Ultraschall.; Handbook
Citation Pointer | 2175021; Journal; Danilow; Tewerowskii; ZETFA7; Zh.Eksp.Teor.Fiz.; 10; 1940; 1305, 1308; Chem.Abstr.; 1941; 5368;

Crystal Phase (7 of 8)

Description | Interplanar spacing
Comment | von kristallinem und von fluessigem Piperin:.; Handbook
Citation Pointer | 981396; Journal; Lewaschewitsch et al.; Trudy Dnetropetrovsk.chim.-technol.Inst.; 4; 1955; 84,88; Chem.Abstr.; 1959; 9760;

Crystal Phase (8 of 8)

Description | Solid state structure properties
Citation Pointer | 3132105; Journal; Grynpas; Lindley; ACBCAR; Acta Crystallogr.Sect.B; 31; 1975; 2663,2664,2665,2666;

Sublimation (1 of 1)

Sublimation | 104
Pressure | 0.02
Comment | Handbook
Citation Pointer | 636409; Journal; Janot; Chaigneau; COREAF; C.R.Hebd.Seances Acad.Sci.; 225; 1947; 1371;

Density of the Liquid (1 of 4)

Density of the Liquid | 1.25
Comment | g/cm**3
Citation Pointer | 3132105; Journal; Grynpas; Lindley; ACBCAR; Acta Crystallogr.Sect.B; 31; 1975; 2663,2664,2665,2666;

Density of the Liquid (2 of 4)

Density of the Liquid | 1.192
Reference Temperature | 4
Measurement Temperature | 20
Comment | Handbook
Citation Pointer | 981390; Journal; Kordes; ZPCBAL; Z.Phys.Chem.Abt.B; 43; 1939; 173,186;

Density of the Liquid (3 of 4)

Density of the Liquid | 1.13
Measurement Temperature | 113
Comment | g/cm**3; Handbook
Citation Pointer | 969752; Journal; Tammann; Tampke; ZAACAB; Z.Anorg.Allg.Chem.; 162; 1927; 10;

Density of the Liquid (4 of 4)

Density of the Liquid | 1.12
Measurement Temperature | 136
Comment | g/cm**3; Handbook
Citation Pointer | 969752; Journal; Tammann; Tampke; ZAACAB; Z.Anorg.Allg.Chem.; 162; 1927; 10;

Dynamic Viscosity (1 of 1)

Dynamic Viscosity | 11.3
Temperature | 95
Comment | Handbook
Citation Pointer | 969749; Journal; Tammann; ZAACAB; Z.Anorg.Allg.Chem.; 181; 1929; 413;969752; Journal; Tammann; Tampke; ZAACAB; Z.Anorg.Allg.Chem.; 162; 1927; 10;969751; Journal; Tammann; Hesse; ZAACAB; Z.Anorg.Allg.Chem.; 156; 1926; 252;

Refractive Index (1 of 1)

Refractive Index | 1.6846
Wavelength | 589
Temperature | 20
Comment | Handbook
Citation Pointer | 981390; Journal; Kordes; ZPCBAL; Z.Phys.Chem.Abt.B; 43; 1939; 173,186;

Nuclear Magnetic Resonance (1 of 15)

Coupling Nuclei | 1H-1H
Solvents | CDCl3
Frequency | 500
Citation Pointer | 6311443; Journal; Schobert, Rainer; Siegfried, Sven; Gordon, Gary J.; JCSPCE; J.Chem.Soc.Perkin Trans.1; EN; 19; 2001; 2393 - 2397;

Nuclear Magnetic Resonance (2 of 15)

Description | Spectrum
Nucleus | 1H
Temperature | 41.9
Citation Pointer | 5945187; Journal; Braumann, Urich; Haendel, heidrun; Albert, Klaus; Ecker, Rainer; Spraul, Manfred; ANCHAM; Anal.Chem.; EN; 67; 5; 1995; 930-935;

Nuclear Magnetic Resonance (3 of 15)

Description | Chemical shifts
Nucleus | 13C
Solvents | CDCl3
Frequency | 125.7
Citation Pointer | 6311443; Journal; Schobert, Rainer; Siegfried, Sven; Gordon, Gary J.; JCSPCE; J.Chem.Soc.Perkin Trans.1; EN; 19; 2001; 2393 - 2397;

Nuclear Magnetic Resonance (4 of 15)

Description | Chemical shifts
Nucleus | 1H
Solvents | CDCl3
Frequency | 500
Citation Pointer | 6311443; Journal; Schobert, Rainer; Siegfried, Sven; Gordon, Gary J.; JCSPCE; J.Chem.Soc.Perkin Trans.1; EN; 19; 2001; 2393 - 2397;

Nuclear Magnetic Resonance (5 of 15)

Description | Chemical shifts
Nucleus | 1H
Solvents | CDCl3
Citation Pointer | 6090513; Journal; Abarbri, Mohamed; Parrain, Jean-Luc; Duchene, Alain; SYNCAV; Synth.Commun.; EN; 28; 2; 1998; 239-250;

Nuclear Magnetic Resonance (6 of 15)

Description | Chemical shifts
Nucleus | 13C
Solvents | CDCl3
Citation Pointer | 6090513; Journal; Abarbri, Mohamed; Parrain, Jean-Luc; Duchene, Alain; SYNCAV; Synth.Commun.; EN; 28; 2; 1998; 239-250;

Nuclear Magnetic Resonance (7 of 15)

Description | Chemical shifts
Nucleus | 1H
Solvents | CDCl3
Citation Pointer | 5864041; Journal; Dahiya, Jagroop S.; Woods, Donald L.; Tewari, Jalpa P.; PYTCAS; Phytochemistry; EN; 27; 7; 1988; 2366;

Nuclear Magnetic Resonance (8 of 15)

Description | Chemical shifts
Nucleus | 13C
Solvents | CDCl3
Citation Pointer | 5787666; Journal; Banerji, Avijit; Sarkar, Manjusha (nee Chaudhuri); Ghosal, Tapasree; Pal, Sudhir Chandra; ORMRBD; Org.Magn.Reson.; EN; 22; 11; 1984; 734-736;

Nuclear Magnetic Resonance (9 of 15)

Description | Chemical shifts
Nucleus | 1H
Solvents | CDCl3
Citation Pointer | 5729448; Journal; Kiuchi, Fumiyuki; Nakamura, Norio; Tsuda, Yoshisuke; Kondo, Kaoru; Yoshimura, Hiroyuki; CPBTAL; Chem.Pharm.Bull.; EN; 36; 7; 1988; 2452-2465;

Nuclear Magnetic Resonance (10 of 15)

Description | Chemical shifts
Nucleus | 13C
Solvents | CDCl3
Citation Pointer | 5576619; Journal; Banerji, Avijit; Ghosal, Tapasree; Acharyya, Aditi K.; IJSBDB; Indian J.Chem.Sect.B; EN; 23; 6; 1984; 546-549;5729448; Journal; Kiuchi, Fumiyuki; Nakamura, Norio; Tsuda, Yoshisuke; Kondo, Kaoru; Yoshimura, Hiroyuki; CPBTAL; Chem.Pharm.Bull.; EN; 36; 7; 1988; 2452-2465;

Nuclear Magnetic Resonance (11 of 15)

Description | 2D-NMR
Citation Pointer | 5945187; Journal; Braumann, Urich; Haendel, heidrun; Albert, Klaus; Ecker, Rainer; Spraul, Manfred; ANCHAM; Anal.Chem.; EN; 67; 5; 1995; 930-935;

Nuclear Magnetic Resonance (12 of 15)

Description | NMR
Citation Pointer | 3143025; Journal; Patra; Gosh; PYTCAS; Phytochemistry; 13; 1974; 2889;3633754; Journal; Wenkert et al.; JACSAT; J.Amer.Chem.Soc.; 93; 1971; 6271;3635101; Journal; De Cleyn; Verzele; BSCBAG; Bull.Soc.Chim.Belg.; 84; 1975; 435,436;

Nuclear Magnetic Resonance (13 of 15)

Description | Spin-spin coupling constants
Solvents | CDCl3
Comment | 1H-1H
Citation Pointer | 5864041; Journal; Dahiya, Jagroop S.; Woods, Donald L.; Tewari, Jalpa P.; PYTCAS; Phytochemistry; EN; 27; 7; 1988; 2366;6090513; Journal; Abarbri, Mohamed; Parrain, Jean-Luc; Duchene, Alain; SYNCAV; Synth.Commun.; EN; 28; 2; 1998; 239-250;

Nuclear Magnetic Resonance (14 of 15)

Description | Spin-spin coupling constants
Solvents | CDCl3
Comment | 1H-13C.
Citation Pointer | 5787666; Journal; Banerji, Avijit; Sarkar, Manjusha (nee Chaudhuri); Ghosal, Tapasree; Pal, Sudhir Chandra; ORMRBD; Org.Magn.Reson.; EN; 22; 11; 1984; 734-736;

Nuclear Magnetic Resonance (15 of 15)

Description | Spin-spin coupling constants
Solvents | CDCl3
Comment | 1H-1H
Citation Pointer | 5729448; Journal; Kiuchi, Fumiyuki; Nakamura, Norio; Tsuda, Yoshisuke; Kondo, Kaoru; Yoshimura, Hiroyuki; CPBTAL; Chem.Pharm.Bull.; EN; 36; 7; 1988; 2452-2465;

Infrared Spectra (1 of 12)

Description | Bands
Solvent | KBr
Citation Pointer | 6311443; Journal; Schobert, Rainer; Siegfried, Sven; Gordon, Gary J.; JCSPCE; J.Chem.Soc.Perkin Trans.1; EN; 19; 2001; 2393 - 2397;

Infrared Spectra (2 of 12)

Description | Bands
Comment | 3058 - 1043 cm**(-1)
Citation Pointer | 6090513; Journal; Abarbri, Mohamed; Parrain, Jean-Luc; Duchene, Alain; SYNCAV; Synth.Commun.; EN; 28; 2; 1998; 239-250;

Infrared Spectra (3 of 12)

Description | Bands
Comment | 1650 - 930 cm**(-1)
Citation Pointer | 5864041; Journal; Dahiya, Jagroop S.; Woods, Donald L.; Tewari, Jalpa P.; PYTCAS; Phytochemistry; EN; 27; 7; 1988; 2366;

Infrared Spectra (4 of 12)

Description | Bands
Solvent | KBr
Comment | 1635 - 925 cm**(-1)
Citation Pointer | 5729448; Journal; Kiuchi, Fumiyuki; Nakamura, Norio; Tsuda, Yoshisuke; Kondo, Kaoru; Yoshimura, Hiroyuki; CPBTAL; Chem.Pharm.Bull.; EN; 36; 7; 1988; 2452-2465;

Infrared Spectra (5 of 12)

Description | Bands
Solvent | CHCl3
Comment | 1635 - 1585 cm**(-1)
Citation Pointer | 5725528; Journal; Nakamura, Norio; Kiuchi, Fumiyuki; Tsuda, Yoshisuke; CPBTAL; Chem.Pharm.Bull.; EN; 36; 7; 1988; 2647-2651;

Infrared Spectra (6 of 12)

Description | Bands
Solvent | KBr
Comment | 1635 - 1585 cm**(-1)
Citation Pointer | 5725528; Journal; Nakamura, Norio; Kiuchi, Fumiyuki; Tsuda, Yoshisuke; CPBTAL; Chem.Pharm.Bull.; EN; 36; 7; 1988; 2647-2651;

Infrared Spectra (7 of 12)

Description | Bands
Solvent | KBr
Comment | 1641 - 1624 cm**(-1)
Citation Pointer | 5571390; Journal; Cabre, Juan; Palomo, Antonio Luis; SYNTBF; Synthesis; EN; 5; 1984; 413-417;

Infrared Spectra (8 of 12)

Description | Bands
Solvent | nujol
Comment | 1600 - 780 cm**(-1); Handbook
Citation Pointer | 642911; Journal; Pleat et al.; JPHAA3; J.Am.Pharm.Assoc.; 40; 1951; 107, 108;

Infrared Spectra (9 of 12)

Description | Bands
Solvent | KBr
Comment | 3020 - 710 cm**(-1); Handbook
Citation Pointer | 511899; Journal; Briggs et al.; ANCHAM; Anal.Chem.; 29; 1957; 904, 905;

Infrared Spectra (10 of 12)

Description | Bands
Solvent | CHCl3
Comment | 1635 - 1580 cm**(-1); Handbook
Citation Pointer | 511899; Journal; Briggs et al.; ANCHAM; Anal.Chem.; 29; 1957; 904, 905;1056240; Journal; Marion et al.; JACSAT; J.Amer.Chem.Soc.; 73; 1951; 305,; JACSAT; J.Amer.Chem.Soc.; 74; 1952; 270;

Infrared Spectra (11 of 12)

Description | Bands
Solvent | CHCl3
Comment | 1490 - 930 cm**(-1); Handbook
Citation Pointer | 511899; Journal; Briggs et al.; ANCHAM; Anal.Chem.; 29; 1957; 904, 905;1056240; Journal; Marion et al.; JACSAT; J.Amer.Chem.Soc.; 73; 1951; 305,; JACSAT; J.Amer.Chem.Soc.; 74; 1952; 270;

Infrared Spectra (12 of 12)

Description | IR
Citation Pointer | 3132150; Journal; Madhusudhana et al.; CUSCAM; Curr.Sci.; 43; 1974; 76;3143025; Journal; Patra; Gosh; PYTCAS; Phytochemistry; 13; 1974; 2889;

Ultraviolet Spectra (1 of 10)

Description | Spectrum
Solvent | CHCl3
Comment | 300 - 400 nm; Handbook
Citation Pointer | 981386; Journal; Tausig et al.; JFOTAP; J.Food Technol.; 10; 1956; 151;

Ultraviolet Spectra (2 of 10)

Description | Spectrum
Solvent | ethanol
Comment | 290 - 380 nm; Handbook
Citation Pointer | 529237; Journal; Spring; Stark; JCSOA9; J.Chem.Soc.; 1950; 1177, 1178;

Ultraviolet Spectra (3 of 10)

Description | Absorption maxima
Absorption Maxima | 341
Ext./Abs. Coefficient | 20893
Citation Pointer | 5864041; Journal; Dahiya, Jagroop S.; Woods, Donald L.; Tewari, Jalpa P.; PYTCAS; Phytochemistry; EN; 27; 7; 1988; 2366;

Ultraviolet Spectra (4 of 10)

Description | Absorption maxima
Solvent | methanol
Absorption Maxima | 309; 341
Citation Pointer | 5749938; Journal; Jain, A. K.; Sharma, N. D.; Gupta, S. R.; IJSBDB; Indian J.Chem.Sect.B; EN; 25; 1986; 979;

Ultraviolet Spectra (5 of 10)

Description | Absorption maxima
Solvent | methanol
Absorption Maxima | 343
Ext./Abs. Coefficient | 34700
Citation Pointer | 5729448; Journal; Kiuchi, Fumiyuki; Nakamura, Norio; Tsuda, Yoshisuke; Kondo, Kaoru; Yoshimura, Hiroyuki; CPBTAL; Chem.Pharm.Bull.; EN; 36; 7; 1988; 2452-2465;

Ultraviolet Spectra (6 of 10)

Description | Absorption maxima
Solvent | methanol
Absorption Maxima | 245; 255; 262; 311
Ext./Abs. Coefficient | 11100; 11200; 11100; 21700
Citation Pointer | 5729448; Journal; Kiuchi, Fumiyuki; Nakamura, Norio; Tsuda, Yoshisuke; Kondo, Kaoru; Yoshimura, Hiroyuki; CPBTAL; Chem.Pharm.Bull.; EN; 36; 7; 1988; 2452-2465;

Ultraviolet Spectra (7 of 10)

Description | Absorption maxima
Citation Pointer | 3635101; Journal; De Cleyn; Verzele; BSCBAG; Bull.Soc.Chim.Belg.; 84; 1975; 435,436;

Ultraviolet Spectra (8 of 10)

Description | Absorption maxima
Comment | des Dampfes.; Handbook
Citation Pointer | 968116; Journal; Purvis; JCSOA9; J.Chem.Soc.; 103; 1913; 2291;

Ultraviolet Spectra (9 of 10)

Description | Absorption maxima
Solvent | ethanol
Comment | Handbook
Citation Pointer | 505581; Journal; Dobbie; Fox; JCSOA9; J.Chem.Soc.; 103; 1913; 1194;

Ultraviolet Spectra (10 of 10)

Description | UV/VIS
Citation Pointer | 3132150; Journal; Madhusudhana et al.; CUSCAM; Curr.Sci.; 43; 1974; 76;3140982; Journal; Grewe et al.; CHBEAM; Chem.Ber.; 103; 1970; 3752,3766;3141492; Journal; Lurik et al.; PCJOAU; Pharm.Chem.J.(Engl.Transl.); 5; 8; 1971; 462; KHFZAN; Khim.Farm.Zh.; 5; 8; 1971; 15;3143025; Journal; Patra; Gosh; PYTCAS; Phytochemistry; 13; 1974; 2889;3714671; Journal; Meerov; Katyuzhanskaya; CHNCA8; Chem.Nat.Compd.(Engl.Transl.); 9; 1973; 179; KPSUAR; Khim.Prir.Soedin.; 9; 1973; 184;

Mass Spectrum (1 of 5)

Citation Pointer | 3140982; Journal; Grewe et al.; CHBEAM; Chem.Ber.; 103; 1970; 3752,3766;3635101; Journal; De Cleyn; Verzele; BSCBAG; Bull.Soc.Chim.Belg.; 84; 1975; 435,436;

Mass Spectrum (2 of 5)

Description | spectrum; electron impact (EI)
Citation Pointer | 6311443; Journal; Schobert, Rainer; Siegfried, Sven; Gordon, Gary J.; JCSPCE; J.Chem.Soc.Perkin Trans.1; EN; 19; 2001; 2393 - 2397;

Mass Spectrum (3 of 5)

Description | spectrum
Citation Pointer | 5864041; Journal; Dahiya, Jagroop S.; Woods, Donald L.; Tewari, Jalpa P.; PYTCAS; Phytochemistry; EN; 27; 7; 1988; 2366;6090513; Journal; Abarbri, Mohamed; Parrain, Jean-Luc; Duchene, Alain; SYNCAV; Synth.Commun.; EN; 28; 2; 1998; 239-250;

Mass Spectrum (4 of 5)

Description | spectrum; electron impact (EI)
Citation Pointer | 5825902; Journal; Semler, Ursula; Gross, Georg G.; PYTCAS; Phytochemistry; EN; 27; 5; 1988; 1566-1568;

Mass Spectrum (5 of 5)

Description | electron impact (EI)
Citation Pointer | 5874363; Journal; Nakamura, Masamichi; Katoh, Kuni; Kawabata, Toshiharu; ABCHA6; Agric.Biol.Chem.; EN; 45; 5; 1981; 1257-1260;

Electrical Data (1 of 1)

Description | Piezoelectricity
Comment | Handbook
Citation Pointer | 536898; Journal; Kopzik et al.; VMUNAE; Vestn.Mosk.Univ.; 13; 6; 1958; 91, 94; Chem.Abstr.; 1959; 15673;

Dissociation Exponent (1 of 3)

Dissociation Exponent (pK) | 14
Temperature | 18
Method | conductometric
Type | apparent
Comment | Handbook
Citation Pointer | 625734; Journal; v. Weisse; Meyer-Levy; JCPBAN; J.Chim.Phys.Phys.Chim.Biol.; 14; 1916; 276; CHZEA6; Chem.Zentralbl.; GE; 87; II; 1916; 1030;

Dissociation Exponent (2 of 3)

Dissociation Exponent (pK) | 12.22
Temperature | 18
Type | b/thermodynamic
Comment | Handbook
Citation Pointer | 740972; Journal; Kolthoff; BIZEA2; Biochem.Z.; 162; 1925; 340; PHJOAV; Pharm.J.; 118; 126; CHZEA6; Chem.Zentralbl.; GE; 98; I; 1927; 2116;

Dissociation Exponent (3 of 3)

Dissociation Exponent (pK) | 11.72
Temperature | 55
Type | b/thermodynamic
Comment | Handbook
Citation Pointer | 625129; Journal; Arnall; JCSOA9; J.Chem.Soc.; 117; 1920; 837;

Electrochemical Characteristics (1 of 1)

Description | polarographic current/voltage curve
Comment | Handbook
Citation Pointer | 981382; Journal; Sato; Japan Analyst; 6; 1957; 83; Chem.Abstr.; 1958; 16088;981383; Journal; Hans; Santavy; C.csl.Lekarn.; 59; 1946; 40; Chem.Abstr.; 1948; 3504;

Solubility (MCS) (1 of 8)

Temperature | 15
Solvent | trichloroethene
Comment | Solubility :9.83 %.; Handbook
Citation Pointer | 559145; Journal; Wester; CHZEA6; Chem.Zentralbl.; GE; 86; I; 1915; 248;

Solubility (MCS) (2 of 8)

Solvent | aq. pyridine
Comment | Solubility :11 %.at:20-25 degreeC.; Handbook
Citation Pointer | 505376; Journal; Dehn; JACSAT; J.Amer.Chem.Soc.; 39; 1917; 1400;

Solubility (MCS) (3 of 8)

Solvent | pyridine
Comment | Solubility :23 %.; Handbook
Citation Pointer | 505376; Journal; Dehn; JACSAT; J.Amer.Chem.Soc.; 39; 1917; 1400;

Solubility (MCS) (4 of 8)

Solvent | ethanol
Comment | 1 part(s) of substance.dissolves in:30 parts of solvent.; Handbook
Citation Pointer | 969748; Journal; Wagenaar; PHWEAW; Pharm.Weekbl.; 66; 1929; 405;

Solubility (MCS) (5 of 8)

Solvent | ethanol
Comment | 1 part(s) of substance.dissolves in:1 parts of solvent.in boiling solvent.; Handbook
Citation Pointer | 969748; Journal; Wagenaar; PHWEAW; Pharm.Weekbl.; 66; 1929; 405;

Solubility (MCS) (6 of 8)

Solvent | ethanol
Comment | 100 g solvent dissolves. 6.66 g Substance.at:20-25 degreeC.; Handbook
Citation Pointer | 562634; Journal; Pucher; Dehn; JACSAT; J.Amer.Chem.Soc.; 43; 1921; 1755;

Solubility (MCS) (7 of 8)

Solubility | 0.04
Saturation | in solution
Temperature | 18
Solvent | H2O
Comment | Handbook
Citation Pointer | 740972; Journal; Kolthoff; BIZEA2; Biochem.Z.; 162; 1925; 340; PHJOAV; Pharm.J.; 118; 126; CHZEA6; Chem.Zentralbl.; GE; 98; I; 1927; 2116;

Solubility (MCS) (8 of 8)

Solubility | 0.4
Saturation | in solution
Temperature | 18
Solvent | aq. HCl
Comment | Handbook
Citation Pointer | 740972; Journal; Kolthoff; BIZEA2; Biochem.Z.; 162; 1925; 340; PHJOAV; Pharm.J.; 118; 126; CHZEA6; Chem.Zentralbl.; GE; 98; I; 1927; 2116;

Boundary Surface Phenomena (MCS) (1 of 1)

Description | Surface tension
Solvent | H2O
Comment | Handbook
Citation Pointer | 625737; Journal; Zeehuisen; AEPPAE; Naunyn-Schmiedeberg's Arch.Exp.Pathol.Pharmakol.; 86; 1920; 366; CHZEA6; Chem.Zentralbl.; GE; 91; III; 1920; 668;

Pharmacological Data (1 of 60)

Citation Pointer | 6318024; Journal; Sunkara, G.; Mada, S. R.; Vobalaboina, V.; PHARAT; Pharmazie; EN; 56; 8; 2001; 640 - 642;

Pharmacological Data (2 of 60)

Citation Pointer | 6318024; Journal; Sunkara, G.; Mada, S. R.; Vobalaboina, V.; PHARAT; Pharmazie; EN; 56; 8; 2001; 640 - 642;

Pharmacological Data (3 of 60)

Citation Pointer | 6318024; Journal; Sunkara, G.; Mada, S. R.; Vobalaboina, V.; PHARAT; Pharmazie; EN; 56; 8; 2001; 640 - 642;

Pharmacological Data (4 of 60)

Citation Pointer | 6318024; Journal; Sunkara, G.; Mada, S. R.; Vobalaboina, V.; PHARAT; Pharmazie; EN; 56; 8; 2001; 640 - 642;

Pharmacological Data (5 of 60)

Citation Pointer | 6318024; Journal; Sunkara, G.; Mada, S. R.; Vobalaboina, V.; PHARAT; Pharmazie; EN; 56; 8; 2001; 640 - 642;

Pharmacological Data (6 of 60)

Citation Pointer | 6318024; Journal; Sunkara, G.; Mada, S. R.; Vobalaboina, V.; PHARAT; Pharmazie; EN; 56; 8; 2001; 640 - 642;

Pharmacological Data (7 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (8 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (9 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (10 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (11 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (12 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (13 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (14 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (15 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (16 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (17 of 60)

Citation Pointer | 6303601; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 3; 2001; 284 - 287;

Pharmacological Data (18 of 60)

Citation Pointer | 6303567; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 2; 2001; 176 - 179;

Pharmacological Data (19 of 60)

Citation Pointer | 6303567; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 2; 2001; 176 - 179;

Pharmacological Data (20 of 60)

Citation Pointer | 6303567; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 2; 2001; 176 - 179;

Pharmacological Data (21 of 60)

Citation Pointer | 6303567; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 2; 2001; 176 - 179;

Pharmacological Data (22 of 60)

Citation Pointer | 6303567; Journal; Bajad, Sunil; Bedi, K. L.; Singla, A. K.; Johri, R. K.; PLMEAA; Planta Med.; EN; 67; 2; 2001; 176 - 179;

Pharmacological Data (23 of 60)

Citation Pointer | 6264052; Journal; Navickiene, Hosana Maria D.; Alecio, Alberto Camilo; Kato, Massuo Jorge; Bolzani, Vanderlan da S.; Young, Maria Claudia M.; Cavalheiro, Alberto Jose; Furlan, Maysa; PYTCAS; Phytochemistry; EN; 55; 2410; 2000; 621 - 626;

Pharmacological Data (24 of 60)

Comment | No effect
Citation Pointer | 6261759; Journal; Rauscher, Frederick M.; Sanders, Ruth A.; Watkins, John B.; JBMTFQ; J.Biochem.Mol.Toxicol.; EN; 14; 6; 2000; 329 - 334;

Pharmacological Data (25 of 60)

Comment | No effect
Citation Pointer | 6261759; Journal; Rauscher, Frederick M.; Sanders, Ruth A.; Watkins, John B.; JBMTFQ; J.Biochem.Mol.Toxicol.; EN; 14; 6; 2000; 329 - 334;

Pharmacological Data (26 of 60)

Citation Pointer | 6261759; Journal; Rauscher, Frederick M.; Sanders, Ruth A.; Watkins, John B.; JBMTFQ; J.Biochem.Mol.Toxicol.; EN; 14; 6; 2000; 329 - 334;

Pharmacological Data (27 of 60)

Citation Pointer | 6261759; Journal; Rauscher, Frederick M.; Sanders, Ruth A.; Watkins, John B.; JBMTFQ; J.Biochem.Mol.Toxicol.; EN; 14; 6; 2000; 329 - 334;

Pharmacological Data (28 of 60)

Citation Pointer | 6261759; Journal; Rauscher, Frederick M.; Sanders, Ruth A.; Watkins, John B.; JBMTFQ; J.Biochem.Mol.Toxicol.; EN; 14; 6; 2000; 329 - 334;

Pharmacological Data (29 of 60)

Citation Pointer | 6261759; Journal; Rauscher, Frederick M.; Sanders, Ruth A.; Watkins, John B.; JBMTFQ; J.Biochem.Mol.Toxicol.; EN; 14; 6; 2000; 329 - 334;

Pharmacological Data (30 of 60)

Citation Pointer | 6261759; Journal; Rauscher, Frederick M.; Sanders, Ruth A.; Watkins, John B.; JBMTFQ; J.Biochem.Mol.Toxicol.; EN; 14; 6; 2000; 329 - 334;

Pharmacological Data (31 of 60)

Citation Pointer | 6261759; Journal; Rauscher, Frederick M.; Sanders, Ruth A.; Watkins, John B.; JBMTFQ; J.Biochem.Mol.Toxicol.; EN; 14; 6; 2000; 329 - 334;

Pharmacological Data (32 of 60)

Citation Pointer | 6261759; Journal; Rauscher, Frederick M.; Sanders, Ruth A.; Watkins, John B.; JBMTFQ; J.Biochem.Mol.Toxicol.; EN; 14; 6; 2000; 329 - 334;

Pharmacological Data (33 of 60)

Citation Pointer | 6261759; Journal; Rauscher, Frederick M.; Sanders, Ruth A.; Watkins, John B.; JBMTFQ; J.Biochem.Mol.Toxicol.; EN; 14; 6; 2000; 329 - 334;

Pharmacological Data (34 of 60)

Citation Pointer | 6235546; Journal; Daware, Mahadeo B.; Mujumdar, Arvind M.; Ghaskadbi, Surendra; PLMEAA; Planta Med.; EN; 66; 3; 2000; 231 - 236;

Pharmacological Data (35 of 60)

Citation Pointer | 6235546; Journal; Daware, Mahadeo B.; Mujumdar, Arvind M.; Ghaskadbi, Surendra; PLMEAA; Planta Med.; EN; 66; 3; 2000; 231 - 236;

Pharmacological Data (36 of 60)

Citation Pointer | 6235546; Journal; Daware, Mahadeo B.; Mujumdar, Arvind M.; Ghaskadbi, Surendra; PLMEAA; Planta Med.; EN; 66; 3; 2000; 231 - 236;

Pharmacological Data (37 of 60)

Citation Pointer | 6235546; Journal; Daware, Mahadeo B.; Mujumdar, Arvind M.; Ghaskadbi, Surendra; PLMEAA; Planta Med.; EN; 66; 3; 2000; 231 - 236;

Pharmacological Data (38 of 60)

Citation Pointer | 6235546; Journal; Daware, Mahadeo B.; Mujumdar, Arvind M.; Ghaskadbi, Surendra; PLMEAA; Planta Med.; EN; 66; 3; 2000; 231 - 236;

Pharmacological Data (39 of 60)

Citation Pointer | 6224648; Journal; Koul, Surrinder; Koul, Jawahir L.; Taneja, Subhash C.; Dhar, Kanaya L.; Jamwal, Deshvir S.; Singh, Kuldeep; Reen, Rashmeet K.; Singh, Jaswant; BMECEP; Bioorg.Med.Chem.; EN; 8; 1; 2000; 251 - 268;

Pharmacological Data (40 of 60)

Citation Pointer | 6224648; Journal; Koul, Surrinder; Koul, Jawahir L.; Taneja, Subhash C.; Dhar, Kanaya L.; Jamwal, Deshvir S.; Singh, Kuldeep; Reen, Rashmeet K.; Singh, Jaswant; BMECEP; Bioorg.Med.Chem.; EN; 8; 1; 2000; 251 - 268;

Pharmacological Data (41 of 60)

Citation Pointer | 6224648; Journal; Koul, Surrinder; Koul, Jawahir L.; Taneja, Subhash C.; Dhar, Kanaya L.; Jamwal, Deshvir S.; Singh, Kuldeep; Reen, Rashmeet K.; Singh, Jaswant; BMECEP; Bioorg.Med.Chem.; EN; 8; 1; 2000; 251 - 268;

Pharmacological Data (42 of 60)

Citation Pointer | 6224648; Journal; Koul, Surrinder; Koul, Jawahir L.; Taneja, Subhash C.; Dhar, Kanaya L.; Jamwal, Deshvir S.; Singh, Kuldeep; Reen, Rashmeet K.; Singh, Jaswant; BMECEP; Bioorg.Med.Chem.; EN; 8; 1; 2000; 251 - 268;

Pharmacological Data (43 of 60)

Citation Pointer | 6224648; Journal; Koul, Surrinder; Koul, Jawahir L.; Taneja, Subhash C.; Dhar, Kanaya L.; Jamwal, Deshvir S.; Singh, Kuldeep; Reen, Rashmeet K.; Singh, Jaswant; BMECEP; Bioorg.Med.Chem.; EN; 8; 1; 2000; 251 - 268;

Pharmacological Data (44 of 60)

Citation Pointer | 6221629; Journal; Kuenzi, Frederick M.; Dale, Nicholas; BJPCBM; Br.J.Pharmacol.; EN; 119; 1; 1996; 81 - 90;

Pharmacological Data (45 of 60)

Citation Pointer | 6202145; Journal; Chu, C.- Y.; Chang, J.-P.; Wang, C.-J.; FCTOD7; Food Chem.Toxicol.; EN; 32; 4; 1994; 373 - 378;

Pharmacological Data (46 of 60)

Citation Pointer | 6202145; Journal; Chu, C.- Y.; Chang, J.-P.; Wang, C.-J.; FCTOD7; Food Chem.Toxicol.; EN; 32; 4; 1994; 373 - 378;

Pharmacological Data (47 of 60)

Citation Pointer | 6199610; Journal; Kang, Min Hee; Won, Sun Me; Park, Sang Shin; Kim, Sang Geon; Novak, R. F.; Kim, Nak Doo; XENOBH; Xenobiotica; EN; 24; 12; 1994; 1195 - 1204;

Pharmacological Data (48 of 60)

Citation Pointer | 6188824; Journal; Unchern, Surachai; Saito, Hiroshi; Nishiyama, Nobuyoshi; BPBLEO; Biol.Pharm.Bull.; EN; 20; 9; 1997; 958 - 961;

Pharmacological Data (49 of 60)

Citation Pointer | 6143346; Journal; Wink, M.; Schmeller, T.; Latz-Bruening, B; JCECD8; J.Chem.Ecol.; EN; 24; 11; 1998; 1881 - 1938;

Pharmacological Data (50 of 60)

Citation Pointer | 6143346; Journal; Wink, M.; Schmeller, T.; Latz-Bruening, B; JCECD8; J.Chem.Ecol.; EN; 24; 11; 1998; 1881 - 1938;

Pharmacological Data (51 of 60)

Citation Pointer | 6143346; Journal; Wink, M.; Schmeller, T.; Latz-Bruening, B; JCECD8; J.Chem.Ecol.; EN; 24; 11; 1998; 1881 - 1938;

Pharmacological Data (52 of 60)

Citation Pointer | 6143346; Journal; Wink, M.; Schmeller, T.; Latz-Bruening, B; JCECD8; J.Chem.Ecol.; EN; 24; 11; 1998; 1881 - 1938;

Pharmacological Data (53 of 60)

Comment | No effect
Citation Pointer | 6143346; Journal; Wink, M.; Schmeller, T.; Latz-Bruening, B; JCECD8; J.Chem.Ecol.; EN; 24; 11; 1998; 1881 - 1938;

Pharmacological Data (54 of 60)

Comment | No effect
Citation Pointer | 6143346; Journal; Wink, M.; Schmeller, T.; Latz-Bruening, B; JCECD8; J.Chem.Ecol.; EN; 24; 11; 1998; 1881 - 1938;

Pharmacological Data (55 of 60)

Comment | No effect
Citation Pointer | 6143346; Journal; Wink, M.; Schmeller, T.; Latz-Bruening, B; JCECD8; J.Chem.Ecol.; EN; 24; 11; 1998; 1881 - 1938;

Pharmacological Data (56 of 60)

Citation Pointer | 6132209; Journal; Singh, Amar; Sharma, S. C.; Zutshi, Usha; Bedi, K. L.; PHSCFB; Pharm.Sci.; EN; 3; 4; 1997; 189 - 192;

Pharmacological Data (57 of 60)

Comment | in vitro anti-invasive activity against MCF-7/6 cells: anti-invasive at a dose 100 mM, not anti-invasive at a dose 1 mM and 10 mM
Citation Pointer | 6073861; Journal; Parmar, Virinder S.; Bracke, Marc E.; Philippe, Jan; Wengel, Jesper; Jain, Subhash C.; et al.; BMECEP; Bioorg.Med.Chem.; EN; 5; 8; 1997; 1609-1620;

Pharmacological Data (58 of 60)

Comment | no effect on the induction of histidine revertants in Salmonella typhimurium in 10 - 500 nmol/plate; no mutagenic effect in the bone marrow micronucleus test in Swiss mice in 10 - 20 mg/kg dose; did not induce any aberration in the sperm cells
Citation Pointer | 6061215; Journal; Karekar, Varsha R.; Mujumdar, Arvind M.; Joshi, Savita S.; Dhuley, Jayant; Shinde, Sambhaji L.; Ghaskadbi, Surendra; ARZNAD; Arzneim.Forsch.; EN; 46; 10; 1996; 972-975;

Pharmacological Data (59 of 60)

Comment | no insecticidal activity against Callosobruchus chinensis L.
Citation Pointer | 5942128; Journal; Miyakado, Masakazu; Nakayama, Isamu; Yoshioka, Hirosuke; ABCHA6; Agric.Biol.Chem.; EN; 44; 7; 1980; 1701-1704;

Pharmacological Data (60 of 60)

Comment | toxicity to mosquito larvae (Culex Spp.); LC50
Citation Pointer | 5510783; Journal; Das, B. P.; Jamal, Molla Yousuf; Choudhury, B.; JICSAH; J.Indian Chem.Soc.; EN; 67; 1; 1990; 72-73;